Espinosa A - Search Results

1

Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds.

Campos JM, Núñez MC, Sánchez RM, Gómez-Vidal JA, Rodríguez-González A, Báñez M, Gallo MA, Lacal JC, Espinosa A. Campos JM, et al. Among authors: espinosa a. Bioorg Med Chem. 2002 Jul;10(7):2215-31. doi: 10.1016/s0968-0896(02)00054-8. Bioorg Med Chem. 2002. PMID: 11983519

2

Inhibition of nNOS activity in rat brain by synthetic kynurenines: structure-activity dependence.

Camacho E, León J, Carrión A, Entrena A, Escames G, Khaldy H, Acuña-Castroviejo D, Gallo MA, Espinosa A. Camacho E, et al. Among authors: espinosa a. J Med Chem. 2002 Jan 17;45(2):263-74. doi: 10.1021/jm010916w. J Med Chem. 2002. PMID: 11784131

3

Synthesis and evaluation of new 5-fluorouracil antitumor cell differentiating derivatives.

Domínguez JF, Marchal JA, Correa A, Carrillo E, Boulaiz H, Aránega A, Gallo MA, Espinosa A. Domínguez JF, et al. Among authors: espinosa a. Bioorg Med Chem. 2003 Feb 6;11(3):315-23. doi: 10.1016/s0968-0896(02)00464-9. Bioorg Med Chem. 2003. PMID: 12517427

4

Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides.

Conejo-García A, Campos J, Sánchez RM, Rodríguez-González A, Lacal JC, Gallo MA, Espinosa A. Conejo-García A, et al. Among authors: espinosa a. Eur J Med Chem. 2003 Jan;38(1):109-16. doi: 10.1016/s0223-5234(02)00004-1. Eur J Med Chem. 2003. PMID: 12593921

5

Anticancer bisquaternary heterocyclic compounds: a ras-ional design.

Campos J, Núñez C, Díaz JJ, Sánchez RM, Gallo MA, Espinosa A. Campos J, et al. Among authors: espinosa a. Farmaco. 2003 Mar;58(3):221-9. doi: 10.1016/S0014-827X(03)00020-X. Farmaco. 2003. PMID: 12620418 Review.

6

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.

Conejo-García A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A. Conejo-García A, et al. Among authors: espinosa a. J Med Chem. 2003 Aug 14;46(17):3754-7. doi: 10.1021/jm030792i. J Med Chem. 2003. PMID: 12904080

7

Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.

Conejo-García A, Báñez-Coronel M, Sánchez-Martín RM, Rodríguez-González A, Ramos A, Ramírez de Molina A, Espinosa A, Gallo MA, Campos JM, Lacal JC. Conejo-García A, et al. Among authors: espinosa a. J Med Chem. 2004 Oct 21;47(22):5433-40. doi: 10.1021/jm0496537. J Med Chem. 2004. PMID: 15481981

8

4,5-dihydro-1H-pyrazole derivatives with inhibitory nNOS activity in rat brain: synthesis and structure-activity relationships.

Camacho ME, León J, Entrena A, Velasco G, Carrión MD, Escames G, Vivó A, Acuña-Castroviejo D, Gallo MA, Espinosa A. Camacho ME, et al. Among authors: espinosa a. J Med Chem. 2004 Nov 4;47(23):5641-50. doi: 10.1021/jm0407714. J Med Chem. 2004. PMID: 15509163

9

Towards a model for the inhibition of choline kinase by a new type of inhibitor.

Conejo-García A, Entrena A, Campos JM, Sánchez-Martín RM, Gallo MA, Espinosa A. Conejo-García A, et al. Among authors: espinosa a. Eur J Med Chem. 2005 Mar;40(3):315-9. doi: 10.1016/j.ejmech.2004.09.016. Epub 2004 Nov 11. Eur J Med Chem. 2005. PMID: 15725501

10

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

Sánchez-Martín R, Campos JM, Conejo-García A, Cruz-López O, Báñez-Coronel M, Rodríguez-González A, Gallo MA, Lacal JC, Espinosa A. Sánchez-Martín R, et al. Among authors: espinosa a. J Med Chem. 2005 May 5;48(9):3354-63. doi: 10.1021/jm049061o. J Med Chem. 2005. PMID: 15857141

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