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Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery.
Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, Dalkara T. Yemisci M, et al. Among authors: can a. Nat Med. 2009 Sep;15(9):1031-7. doi: 10.1038/nm.2022. Epub 2009 Aug 30. Nat Med. 2009. PMID: 19718040
We also show that the microvessel wall is the major source of oxygen and nitrogen radicals causing ischemia and reperfusion-induced microvascular dysfunction. These findings point to a major but previously not recognized pathophysiological mechanism; ischemia and reperfusi …
We also show that the microvessel wall is the major source of oxygen and nitrogen radicals causing ischemia and reperfusion-induced microvas …
Inadequate brain glycogen or sleep increases spreading depression susceptibility.
Kilic K, Karatas H, Dönmez-Demir B, Eren-Kocak E, Gursoy-Ozdemir Y, Can A, Petit JM, Magistretti PJ, Dalkara T. Kilic K, et al. Among authors: can a. Ann Neurol. 2018 Jan;83(1):61-73. doi: 10.1002/ana.25122. Ann Neurol. 2018. PMID: 29244233
OBJECTIVE: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K(+) concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional changes in astrocytes, reducing glycogen brea …
OBJECTIVE: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K(+) concentrations around excitato …
384 results