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Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.
Letavic MA, Axt MZ, Barberia JT, Carty TJ, Danley DE, Geoghegan KF, Halim NS, Hoth LR, Kamath AV, Laird ER, Lopresti-Morrow LL, McClure KF, Mitchell PG, Natarajan V, Noe MC, Pandit J, Reeves L, Schulte GK, Snow SL, Sweeney FJ, Tan DH, Yu CH. Letavic MA, et al. Among authors: axt mz. Bioorg Med Chem Lett. 2002 May 20;12(10):1387-90. doi: 10.1016/s0960-894x(02)00183-x. Bioorg Med Chem Lett. 2002. PMID: 11992783
Alkylation of succinates: synthesis of Ro 32-3555.
McClure KF, Axt MZ. McClure KF, et al. Among authors: axt mz. Bioorg Med Chem Lett. 1998 Jan 20;8(2):143-6. doi: 10.1016/s0960-894x(97)10179-2. Bioorg Med Chem Lett. 1998. PMID: 9871642