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Page 1
Anthrax lethal factor inhibition.
Shoop WL, Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Felcetto T, Michael BF, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Patel SB, Wisniewski D, Scapin G, Salowe SP, Zaller DM, Chapman KT, Scolnick EM, Schmatz DM, Bartizal K, MacCoss M, Hermes JD. Shoop WL, et al. Among authors: wiltsie j. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7958-63. doi: 10.1073/pnas.0502159102. Epub 2005 May 23. Proc Natl Acad Sci U S A. 2005. PMID: 15911756 Free PMC article.
The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.
Xiong Y, Wiltsie J, Woods A, Guo J, Pivnichny JV, Tang W, Bansal A, Cummings RT, Cunningham BR, Friedlander AM, Douglas CM, Salowe SP, Zaller DM, Scolnick EM, Schmatz DM, Bartizal K, Hermes JD, MacCoss M, Chapman KT. Xiong Y, et al. Among authors: wiltsie j. Bioorg Med Chem Lett. 2006 Feb 15;16(4):964-8. doi: 10.1016/j.bmcl.2005.10.088. Epub 2005 Dec 9. Bioorg Med Chem Lett. 2006. PMID: 16338135
The role of a parasite-specific allosteric site in the distinctive activation behavior of Eimeria tenella cGMP-dependent protein kinase.
Salowe SP, Wiltsie J, Liberator PA, Donald RG. Salowe SP, et al. Among authors: wiltsie j. Biochemistry. 2002 Apr 2;41(13):4385-91. doi: 10.1021/bi0156658. Biochemistry. 2002. PMID: 11914085
A., Dulski, P., Salowe, S., Donald, R. G. K., Anderson, J., Wiltsie, J., Diaz, C., Harris, G., Chang, B., Darkin-Rattray, S. J., Nare, B., Crumley, T., Blum, P., Misura, A., Tamas, T., Sardana, M., Yuan, J., Biftu, T., and Schmatz, D. (2002) …
A., Dulski, P., Salowe, S., Donald, R. G. K., Anderson, J., Wiltsie, J., Diaz, C., Harris, G., Chang, B., Darkin-Rattra …
In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors.
Salowe SP, Zhang L, Zokian HJ, Gesell JJ, Zink DL, Wiltsie J, Ai X, Kavana M, Pinto S. Salowe SP, et al. Among authors: wiltsie j. J Biomol Screen. 2016 Dec;21(10):1034-1041. doi: 10.1177/1087057116657312. Epub 2016 Jul 11. J Biomol Screen. 2016. PMID: 27412534
Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target.
Gurnett AM, Liberator PA, Dulski PM, Salowe SP, Donald RG, Anderson JW, Wiltsie J, Diaz CA, Harris G, Chang B, Darkin-Rattray SJ, Nare B, Crumley T, Blum PS, Misura AS, Tamas T, Sardana MK, Yuan J, Biftu T, Schmatz DM. Gurnett AM, et al. Among authors: wiltsie j. J Biol Chem. 2002 May 3;277(18):15913-22. doi: 10.1074/jbc.M108393200. Epub 2002 Feb 7. J Biol Chem. 2002. PMID: 11834729 Free article.
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus.
Phillips JW, Goetz MA, Smith SK, Zink DL, Polishook J, Onishi R, Salowe S, Wiltsie J, Allocco J, Sigmund J, Dorso K, Lee S, Skwish S, de la Cruz M, Martín J, Vicente F, Genilloud O, Lu J, Painter RE, Young K, Overbye K, Donald RG, Singh SB. Phillips JW, et al. Among authors: wiltsie j. Chem Biol. 2011 Aug 26;18(8):955-65. doi: 10.1016/j.chembiol.2011.06.011. Chem Biol. 2011. PMID: 21867911
Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities.
Singh SB, Goetz MA, Smith SK, Zink DL, Polishook J, Onishi R, Salowe S, Wiltsie J, Allocco J, Sigmund J, Dorso K, de la Cruz M, Martín J, Vicente F, Genilloud O, Donald RG, Phillips JW. Singh SB, et al. Among authors: wiltsie j. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7127-30. doi: 10.1016/j.bmcl.2012.09.071. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23084277
39 results