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Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database.
Ruelle J, Roman F, Vandenbroucke AT, Lambert C, Fransen K, Echahidi F, Piérard D, Verhofstede C, Van Laethem K, Delforge ML, Vaira D, Schmit JC, Goubau P. Ruelle J, et al. Among authors: fransen k. BMC Infect Dis. 2008 Feb 27;8:21. doi: 10.1186/1471-2334-8-21. BMC Infect Dis. 2008. PMID: 18304321 Free PMC article.
Virologic therapy response significantly correlates with the number of active drugs as evaluated using a LiPA HIV-1 resistance scoring system.
Ziermann R, Celis L, Derdelinckx I, Lambert C, Veeck J, Rizzo MG, Vanderborght B, Zissis G, Clumeck N, Fransen K, Vaira D, Hendricks D, Van Laethem K, Vandamme AM, Schmit JC, Knechten H, De Luca A, Louwagie J, Segers P, De Boeck K, Pottel H, De Brauwer A, Hulstaert F. Ziermann R, et al. Among authors: fransen k. J Clin Virol. 2004 Dec;31 Suppl 1:S7-15. doi: 10.1016/j.jcv.2004.09.014. J Clin Virol. 2004. PMID: 15567089 Free article.
Chronic and Early Antiretroviral Therapy Impact Human Immunodeficiency Virus (HIV) Serological Assay Sensitivity, Leading to More False-Negative Test Results in HIV Diagnosis.
Stoffels K, Vanroye F, Mortier V, Debaisieux L, Delforge ML, Depypere M, Dessilly G, Vaira D, Vancutsem E, Van den Wijngaert S, Van Laethem K, Vercauteren KOA, Verhofstede C, Fransen K. Stoffels K, et al. Among authors: fransen k. J Infect Dis. 2020 Oct 13;222(10):1660-1669. doi: 10.1093/infdis/jiaa271. J Infect Dis. 2020. PMID: 32433757
Performance of the VERSANT HIV-1 resistance assays (LiPA) for detecting drug resistance in therapy-naive patients infected with different HIV-1 subtypes.
Derdelinckx I, Van Laethem K, Maes B, Schrooten Y, De Schouwer K, De Wit S, Fransen K, García Ribas S, Moutschen M, Vaira D, Zissis G, Van Ranst M, Van Wijngaerden E, Vandamme AM. Derdelinckx I, et al. Among authors: fransen k. FEMS Immunol Med Microbiol. 2003 Nov 28;39(2):119-24. doi: 10.1016/S0928-8244(03)00240-2. FEMS Immunol Med Microbiol. 2003. PMID: 14625094 Free article.
Current levels of drug resistance among therapy-naive HIV-infected patients have significant impact on treatment response.
Derdelinckx I, Van Laethem K, Maes B, Schrooten Y, De Wit S, Florence E, Fransen K, Ribas SG, Marissens D, Moutschen M, Vaira D, Zissis G, Van Ranst M, Van Wijngaerden E, Vandamme AM. Derdelinckx I, et al. Among authors: fransen k. J Acquir Immune Defic Syndr. 2004 Dec 15;37(5):1664-6. doi: 10.1097/00126334-200412150-00022. J Acquir Immune Defic Syndr. 2004. PMID: 15577426 Free article. Clinical Trial. No abstract available.
Prevalence and epidemiology of HIV type 1 drug resistance among newly diagnosed therapy-naive patients in Belgium from 2003 to 2006.
Vercauteren J, Derdelinckx I, Sasse A, Bogaert M, Ceunen H, De Roo A, De Wit S, Deforche K, Echahidi F, Fransen K, Goffard JC, Goubau P, Goudeseune E, Yombi JC, Lacor P, Liesnard C, Moutschen M, Pierard D, Rens R, Schrooten Y, Vaira D, van den Heuvel A, van der Gucht B, van Ranst M, van Wijngaerden E, Vandercam B, Vekemans M, Verhofstede C, Clumeck N, Vandamme AM, van Laethem K. Vercauteren J, et al. Among authors: fransen k. AIDS Res Hum Retroviruses. 2008 Mar;24(3):355-62. doi: 10.1089/aid.2007.0212. AIDS Res Hum Retroviruses. 2008. PMID: 18327983
Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.
Vandekerckhove L, Verhofstede C, Demecheleer E, De Wit S, Florence E, Fransen K, Moutschen M, Mostmans W, Kabeya K, Mackie N, Plum J, Vaira D, Van Baelen K, Vandenbroucke I, Van Eygen V, Van Marck H, Vogelaers D, Geretti AM, Stuyver LJ. Vandekerckhove L, et al. Among authors: fransen k. J Antimicrob Chemother. 2011 Feb;66(2):265-72. doi: 10.1093/jac/dkq458. Epub 2010 Dec 31. J Antimicrob Chemother. 2011. PMID: 21196489 Free PMC article.
Decision tree for accurate infection timing in individuals newly diagnosed with HIV-1 infection.
Verhofstede C, Fransen K, Van Den Heuvel A, Van Laethem K, Ruelle J, Vancutsem E, Stoffels K, Van den Wijngaert S, Delforge ML, Vaira D, Hebberecht L, Schauvliege M, Mortier V, Dauwe K, Callens S. Verhofstede C, et al. Among authors: fransen k. BMC Infect Dis. 2017 Nov 29;17(1):738. doi: 10.1186/s12879-017-2850-6. BMC Infect Dis. 2017. PMID: 29187159 Free PMC article.
Phylogenetic analysis of the Belgian HIV-1 epidemic reveals that local transmission is almost exclusively driven by men having sex with men despite presence of large African migrant communities.
Verhofstede C, Dauwe K, Fransen K, Van Laethem K, Van den Wijngaert S, Ruelle J, Delforge ML, Vancutsem E, Vaira D, Stoffels K, Ribas SG, Dessilly G, Debaisieux L, Pierard D, Van Ranst M, Hayette MP, Deblonde J, Sasse A, Van Beckhoven D, Mortier V. Verhofstede C, et al. Among authors: fransen k. Infect Genet Evol. 2018 Jul;61:36-44. doi: 10.1016/j.meegid.2018.03.002. Epub 2018 Mar 6. Infect Genet Evol. 2018. PMID: 29522828 Free article.
252 results