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Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin.
Kane NS, Hirschberg B, Qian S, Hunt D, Thomas B, Brochu R, Ludmerer SW, Zheng Y, Smith M, Arena JP, Cohen CJ, Schmatz D, Warmke J, Cully DF. Kane NS, et al. Among authors: ludmerer sw. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13949-54. doi: 10.1073/pnas.240464697. Proc Natl Acad Sci U S A. 2000. PMID: 11095718 Free PMC article.
Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity.
Coburn CA, Meinke PT, Chang W, Fandozzi CM, Graham DJ, Hu B, Huang Q, Kargman S, Kozlowski J, Liu R, McCauley JA, Nomeir AA, Soll RM, Vacca JP, Wang D, Wu H, Zhong B, Olsen DB, Ludmerer SW. Coburn CA, et al. Among authors: ludmerer sw. ChemMedChem. 2013 Dec;8(12):1930-40. doi: 10.1002/cmdc.201300343. Epub 2013 Oct 14. ChemMedChem. 2013. PMID: 24127258
44 results