Boyd H - Search Results

1

Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-beta-lactamases.

Payne DJ, Hueso-Rodríguez JA, Boyd H, Concha NO, Janson CA, Gilpin M, Bateson JH, Cheever C, Niconovich NL, Pearson S, Rittenhouse S, Tew D, Díez E, Pérez P, De La Fuente J, Rees M, Rivera-Sagredo A. Payne DJ, et al. Among authors: boyd h. Antimicrob Agents Chemother. 2002 Jun;46(6):1880-6. doi: 10.1128/AAC.46.6.1880-1886.2002. Antimicrob Agents Chemother. 2002. PMID: 12019104 Free PMC article.

2

SB-253514 and analogues; novel inhibitors of lipoprotein-associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. I. Fermentation of producing strain, isolation and biological activity.

Thirkettle J, Alvarez E, Boyd H, Brown M, Diez E, Hueso J, Elson S, Fulston M, Gershater C, Morata ML, Perez P, Ready S, Sanchez-Puelles JM, Sheridan R, Stefanska A, Warr S. Thirkettle J, et al. Among authors: boyd h. J Antibiot (Tokyo). 2000 Jul;53(7):664-9. doi: 10.7164/antibiotics.53.664. J Antibiot (Tokyo). 2000. PMID: 10994807 Free article.

3

Nanomolar inhibitors of Staphylococcus aureus methionyl tRNA synthetase with potent antibacterial activity against gram-positive pathogens.

Jarvest RL, Berge JM, Berry V, Boyd HF, Brown MJ, Elder JS, Forrest AK, Fosberry AP, Gentry DR, Hibbs MJ, Jaworski DD, O'Hanlon PJ, Pope AJ, Rittenhouse S, Sheppard RJ, Slater-Radosti C, Worby A. Jarvest RL, et al. J Med Chem. 2002 May 9;45(10):1959-62. doi: 10.1021/jm025502x. J Med Chem. 2002. PMID: 11985462

4

Mechanism of inhibition of LDL phospholipase A2 by monocyclic-beta-lactams. Burst kinetics and the effect of stereochemistry.

Tew DG, Boyd HF, Ashman S, Theobald C, Leach CA. Tew DG, et al. Among authors: boyd hf. Biochemistry. 1998 Jul 14;37(28):10087-93. doi: 10.1021/bi9801412. Biochemistry. 1998. PMID: 9665713

5

Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor.

MacPhee CH, Moores KE, Boyd HF, Dhanak D, Ife RJ, Leach CA, Leake DS, Milliner KJ, Patterson RA, Suckling KE, Tew DG, Hickey DM. MacPhee CH, et al. Among authors: boyd hf. Biochem J. 1999 Mar 1;338 ( Pt 2)(Pt 2):479-87. Biochem J. 1999. PMID: 10024526 Free PMC article.

6

N-1 substituted pyrimidin-4-ones: novel, orally active inhibitors of lipoprotein-associated phospholipase A2.

Boyd HF, Fell SC, Flynn ST, Hickey DM, Ife RJ, Leach CA, Macphee CH, Milliner KJ, Moores KE, Pinto IL, Porter RA, Rawlings DA, Smith SA, Stansfield IG, Tew DG, Theobald CJ, Whittaker CM. Boyd HF, et al. Bioorg Med Chem Lett. 2000 Nov 20;10(22):2557-61. doi: 10.1016/s0960-894x(00)00510-2. Bioorg Med Chem Lett. 2000. PMID: 11086729

7

Expression, purification and characterization of a human serine-dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor.

Rice SQ, Southan C, Boyd HF, Terrett JA, MacPhee CH, Moores K, Gloger IS, Tew DG. Rice SQ, et al. Among authors: boyd hf. Biochem J. 1998 Mar 15;330 ( Pt 3)(Pt 3):1309-15. doi: 10.1042/bj3301309. Biochem J. 1998. PMID: 9494101 Free PMC article.

8

Natural product derived inhibitors of lipoprotein associated phospholipase A2, synthesis and activity of analogues of SB-253514.

Pinto IL, Boyd HF, Hickey DM. Pinto IL, et al. Among authors: boyd hf. Bioorg Med Chem Lett. 2000 Sep 4;10(17):2015-7. doi: 10.1016/s0960-894x(00)00395-4. Bioorg Med Chem Lett. 2000. PMID: 10987439

9

Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins.

Tew DG, Southan C, Rice SQ, Lawrence MP, Li H, Boyd HF, Moores K, Gloger IS, Macphee CH. Tew DG, et al. Among authors: boyd hf. Arterioscler Thromb Vasc Biol. 1996 Apr;16(4):591-9. doi: 10.1161/01.atv.16.4.591. Arterioscler Thromb Vasc Biol. 1996. PMID: 8624782

10

The role of ATP citrate-lyase in the metabolic regulation of plasma lipids. Hypolipidaemic effects of SB-204990, a lactone prodrug of the potent ATP citrate-lyase inhibitor SB-201076.

Pearce NJ, Yates JW, Berkhout TA, Jackson B, Tew D, Boyd H, Camilleri P, Sweeney P, Gribble AD, Shaw A, Groot PH. Pearce NJ, et al. Among authors: boyd h. Biochem J. 1998 Aug 15;334 ( Pt 1)(Pt 1):113-9. doi: 10.1042/bj3340113. Biochem J. 1998. PMID: 9693110 Free PMC article.

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