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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW. Parham C, et al. Among authors: mcclanahan t. J Immunol. 2002 Jun 1;168(11):5699-708. doi: 10.4049/jimmunol.168.11.5699. J Immunol. 2002. PMID: 12023369
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells.
Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, Blumenschein WM, Mattson JD, Wagner JL, To W, Zurawski S, McClanahan TK, Gorman DM, Bazan JF, de Waal Malefyt R, Rennick D, Kastelein RA. Pflanz S, et al. Among authors: mcclanahan tk. Immunity. 2002 Jun;16(6):779-90. doi: 10.1016/s1074-7613(02)00324-2. Immunity. 2002. PMID: 12121660 Free article.
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells.
Diveu C, McGeachy MJ, Boniface K, Stumhofer JS, Sathe M, Joyce-Shaikh B, Chen Y, Tato CM, McClanahan TK, de Waal Malefyt R, Hunter CA, Cua DJ, Kastelein RA. Diveu C, et al. J Immunol. 2009 May 1;182(9):5748-56. doi: 10.4049/jimmunol.0801162. J Immunol. 2009. PMID: 19380822
IL-33 induces IL-13-dependent cutaneous fibrosis.
Rankin AL, Mumm JB, Murphy E, Turner S, Yu N, McClanahan TK, Bourne PA, Pierce RH, Kastelein R, Pflanz S. Rankin AL, et al. J Immunol. 2010 Feb 1;184(3):1526-35. doi: 10.4049/jimmunol.0903306. Epub 2009 Dec 30. J Immunol. 2010. PMID: 20042577
236 results