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Astrocytes produce and secrete FGF-1, which promotes the production of apoE-HDL in a manner of autocrine action.
Ito J, Nagayasu Y, Lu R, Kheirollah A, Hayashi M, Yokoyama S. Ito J, et al. J Lipid Res. 2005 Apr;46(4):679-86. doi: 10.1194/jlr.M400313-JLR200. Epub 2005 Jan 1. J Lipid Res. 2005. PMID: 15627653 Free article.
The astrocytes prepared by 1 week secondary culture after 1 month primary culture of rat brain cells (M/W cells) synthesized and secreted apolipoprotein E (apoE) and cholesterol more than the astrocytes prepared by conventional 1 week primary and 1 week secondary culture (W/W cel …
The astrocytes prepared by 1 week secondary culture after 1 month primary culture of rat brain cells (M/W cells) synthesized and secreted ap …
Cyclosporin A inhibits apolipoprotein A-I-induced early events in cellular cholesterol homeostasis in rat astrocytes.
Kheirollah A, Ito J, Nagayasu Y, Lu R, Yokoyama S. Kheirollah A, et al. Among authors: ito j. Neuropharmacology. 2006 Sep;51(4):693-700. doi: 10.1016/j.neuropharm.2006.04.020. Epub 2006 Jul 11. Neuropharmacology. 2006. PMID: 16815483
In the biogenesis of HDL by exogenous apolipoprotein (apo) A-I in rat astrocytes, apoA-I induced translocation of phospholipase Cgamma (PLCgamma) and PKCalpha to cytosolic lipid protein particle (CLPP) [Ito et al., 2004. J. Lipid Res. 45, 2269] and caused tyrosine-p …
In the biogenesis of HDL by exogenous apolipoprotein (apo) A-I in rat astrocytes, apoA-I induced translocation of phospholipase Cgamma (PLCg …
Mechanism for FGF-1 to regulate biogenesis of apoE-HDL in astrocytes.
Ito J, Nagayasu Y, Okumura-Noji K, Lu R, Nishida T, Miura Y, Asai K, Kheirollah A, Nakaya S, Yokoyama S. Ito J, et al. J Lipid Res. 2007 Sep;48(9):2020-7. doi: 10.1194/jlr.M700188-JLR200. Epub 2007 Jun 4. J Lipid Res. 2007. PMID: 17548887 Free article.
1,926 results