Chan DC - Search Results

1

Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels.

Singh RP, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Singh RP, et al. Among authors: chan dc. Cancer Res. 2002 Jun 1;62(11):3063-9. Cancer Res. 2002. PMID: 12036915

2

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling.

Singh RP, Raina K, Deep G, Chan D, Agarwal R. Singh RP, et al. Clin Cancer Res. 2009 Jan 15;15(2):613-21. doi: 10.1158/1078-0432.CCR-08-1846. Clin Cancer Res. 2009. PMID: 19147767 Free PMC article.

3

Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis.

Tyagi AK, Singh RP, Agarwal C, Chan DC, Agarwal R. Tyagi AK, et al. Among authors: chan dc. Clin Cancer Res. 2002 Nov;8(11):3512-9. Clin Cancer Res. 2002. PMID: 12429642

4

Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells.

Tyagi AK, Agarwal C, Chan DC, Agarwal R. Tyagi AK, et al. Among authors: chan dc. Oncol Rep. 2004 Feb;11(2):493-9. Oncol Rep. 2004. PMID: 14719089

5

Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells.

Sharma G, Tyagi AK, Singh RP, Chan DC, Agarwal R. Sharma G, et al. Among authors: chan dc. Breast Cancer Res Treat. 2004 May;85(1):1-12. doi: 10.1023/B:BREA.0000020991.55659.59. Breast Cancer Res Treat. 2004. PMID: 15039593

6

Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance.

Singh RP, Mallikarjuna GU, Sharma G, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Singh RP, et al. Among authors: chan dc. Clin Cancer Res. 2004 Dec 15;10(24):8641-7. doi: 10.1158/1078-0432.CCR-04-1435. Clin Cancer Res. 2004. PMID: 15623648

7

Silibinin induces growth inhibition and apoptotic cell death in human lung carcinoma cells.

Sharma G, Singh RP, Chan DC, Agarwal R. Sharma G, et al. Among authors: chan dc. Anticancer Res. 2003 May-Jun;23(3B):2649-55. Anticancer Res. 2003. PMID: 12894553

8

Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells.

Mateen S, Raina K, Agarwal C, Chan D, Agarwal R. Mateen S, et al. J Pharmacol Exp Ther. 2013 May;345(2):206-14. doi: 10.1124/jpet.113.203471. Epub 2013 Mar 5. J Pharmacol Exp Ther. 2013. PMID: 23461975 Free PMC article.

9

Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells.

Mateen S, Raina K, Jain AK, Agarwal C, Chan D, Agarwal R. Mateen S, et al. Epigenetics. 2012 Oct;7(10):1161-72. doi: 10.4161/epi.22070. Epub 2012 Sep 10. Epigenetics. 2012. PMID: 22965008 Free PMC article.

10

Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors.

Chan DC, Earle KA, Zhao TL, Helfrich B, Zeng C, Baron A, Whitehead CM, Piazza G, Pamukcu R, Thompson WJ, Alila H, Nelson P, Bunn PA Jr. Chan DC, et al. Clin Cancer Res. 2002 Mar;8(3):904-12. Clin Cancer Res. 2002. PMID: 11895925

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