Yan H - Search Results

1

Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

Gu Y, Reshetnikova L, Li Y, Wu Y, Yan H, Singh S, Ji X. Gu Y, et al. Among authors: yan h. J Mol Biol. 2002 Jun 7;319(3):779-89. doi: 10.1016/S0022-2836(02)00339-X. J Mol Biol. 2002. PMID: 12054870

2

Essential roles of a dynamic loop in the catalysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Blaszczyk J, Li Y, Wu Y, Shi G, Ji X, Yan H. Blaszczyk J, et al. Among authors: yan h. Biochemistry. 2004 Feb 17;43(6):1469-77. doi: 10.1021/bi036053l. Biochemistry. 2004. PMID: 14769023

3

Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimic acid and an ATP analogue.

Gan J, Gu Y, Li Y, Yan H, Ji X. Gan J, et al. Among authors: yan h. Biochemistry. 2006 Jul 18;45(28):8539-45. doi: 10.1021/bi0606290. Biochemistry. 2006. PMID: 16834327

4

Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase.

Blaszczyk J, Li Y, Gan J, Yan H, Ji X. Blaszczyk J, et al. Among authors: yan h. J Mol Biol. 2007 Apr 20;368(1):161-9. doi: 10.1016/j.jmb.2007.02.009. Epub 2007 Feb 9. J Mol Biol. 2007. PMID: 17331536 Free PMC article.

5

Structural and biochemical analyses of shikimate dehydrogenase AroE from Aquifex aeolicus: implications for the catalytic mechanism.

Gan J, Wu Y, Prabakaran P, Gu Y, Li Y, Andrykovitch M, Liu H, Gong Y, Yan H, Ji X. Gan J, et al. Among authors: yan h. Biochemistry. 2007 Aug 21;46(33):9513-22. doi: 10.1021/bi602601e. Epub 2007 Jul 25. Biochemistry. 2007. PMID: 17649975

6

Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: crystallographic studies.

Blaszczyk J, Li Y, Shi G, Yan H, Ji X. Blaszczyk J, et al. Among authors: yan h. Biochemistry. 2003 Feb 18;42(6):1573-80. doi: 10.1021/bi0267994. Biochemistry. 2003. PMID: 12578370

7

Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.

Blaszczyk J, Shi G, Li Y, Yan H, Ji X. Blaszczyk J, et al. Among authors: yan h. Structure. 2004 Mar;12(3):467-75. doi: 10.1016/j.str.2004.02.003. Structure. 2004. PMID: 15016362 Free article.

8

Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.

Blaszczyk J, Li Y, Cherry S, Alexandratos J, Wu Y, Shaw G, Tropea JE, Waugh DS, Yan H, Ji X. Blaszczyk J, et al. Among authors: yan h. Acta Crystallogr D Biol Crystallogr. 2007 Nov;63(Pt 11):1169-77. doi: 10.1107/S0907444907047452. Epub 2007 Oct 17. Acta Crystallogr D Biol Crystallogr. 2007. PMID: 18007032

9

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties.

Shi G, Shaw G, Liang YH, Subburaman P, Li Y, Wu Y, Yan H, Ji X. Shi G, et al. Among authors: yan h. Bioorg Med Chem. 2012 Jan 1;20(1):47-57. doi: 10.1016/j.bmc.2011.11.032. Epub 2011 Nov 23. Bioorg Med Chem. 2012. PMID: 22169600 Free PMC article.

10

Bisubstrate analog inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: new lead exhibits a distinct binding mode.

Shi G, Shaw G, Li Y, Wu Y, Yan H, Ji X. Shi G, et al. Among authors: yan h. Bioorg Med Chem. 2012 Jul 15;20(14):4303-9. doi: 10.1016/j.bmc.2012.05.060. Epub 2012 Jun 6. Bioorg Med Chem. 2012. PMID: 22727779 Free PMC article.

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