Agrawal S - Search Results

1

Antisense oligonucleotide targeted to RIalpha subunit of cAMP-dependent protein kinase (GEM231) enhances therapeutic effectiveness of cancer chemotherapeutic agent irinotecan in nude mice bearing human cancer xenografts: in vivo synergistic activity, pharmacokinetics and host toxicity.

Wang H, Hang J, Shi Z, Li M, Yu D, Kandimalla ER, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Int J Oncol. 2002 Jul;21(1):73-80. Int J Oncol. 2002. PMID: 12063552

2

Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms.

Wang H, Oliver P, Zhang Z, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Ann N Y Acad Sci. 2003 Dec;1002:217-35. doi: 10.1196/annals.1281.025. Ann N Y Acad Sci. 2003. PMID: 14751837

3

Radiosensitization by antisense anti-MDM2 mixed-backbone oligonucleotide in in vitro and in vivo human cancer models.

Zhang Z, Wang H, Prasad G, Li M, Yu D, Bonner JA, Agrawal S, Zhang R. Zhang Z, et al. Among authors: agrawal s. Clin Cancer Res. 2004 Feb 15;10(4):1263-73. doi: 10.1158/1078-0432.ccr-0245-03. Clin Cancer Res. 2004. PMID: 14977824

4

Novel antisense anti-MDM2 mixed-backbone oligonucleotides: proof of principle, in vitro and in vivo activities, and mechanisms.

Zhang R, Wang H, Agrawal S. Zhang R, et al. Among authors: agrawal s. Curr Cancer Drug Targets. 2005 Feb;5(1):43-9. doi: 10.2174/1568009053332663. Curr Cancer Drug Targets. 2005. PMID: 15720188 Review.

5

Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9.

Wang H, Rayburn ER, Wang W, Kandimalla ER, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Mol Cancer Ther. 2006 Jun;5(6):1585-92. doi: 10.1158/1535-7163.MCT-06-0094. Mol Cancer Ther. 2006. PMID: 16818518

6

Immunomodulatory oligonucleotides as novel therapy for breast cancer: pharmacokinetics, in vitro and in vivo anticancer activity, and potentiation of antibody therapy.

Wang H, Rayburn ER, Wang W, Kandimalla ER, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Mol Cancer Ther. 2006 Aug;5(8):2106-14. doi: 10.1158/1535-7163.MCT-06-0158. Mol Cancer Ther. 2006. PMID: 16928832

7

GEM 231, a second-generation antisense agent complementary to protein kinase A RIalpha subunit, potentiates antitumor activity of irinotecan in human colon, pancreas, prostate and lung cancer xenografts.

Agrawal S, Kandimalla ER, Yu D, Ball R, Lombardi G, Lucas T, Dexter DL, Hollister BA, Chen SF. Agrawal S, et al. Int J Oncol. 2002 Jul;21(1):65-72. Int J Oncol. 2002. PMID: 12063551

8

Anti-tumor efficacy of a novel antisense anti-MDM2 mixed-backbone oligonucleotide in human colon cancer models: p53-dependent and p53-independent mechanisms.

Wang H, Nan L, Yu D, Lindsey JR, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Mol Med. 2002 Apr;8(4):185-99. Mol Med. 2002. PMID: 12149568 Free PMC article.

9

Experimental therapy of human prostate cancer by inhibiting MDM2 expression with novel mixed-backbone antisense oligonucleotides: in vitro and in vivo activities and mechanisms.

Wang H, Yu D, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Prostate. 2003 Feb 15;54(3):194-205. doi: 10.1002/pros.10187. Prostate. 2003. PMID: 12518324

10

Antisense anti-MDM2 mixed-backbone oligonucleotides enhance therapeutic efficacy of topoisomerase I inhibitor irinotecan in nude mice bearing human cancer xenografts: In vivo activity and mechanisms.

Wang H, Wang S, Nan L, Yu D, Agrawal S, Zhang R. Wang H, et al. Among authors: agrawal s. Int J Oncol. 2002 Apr;20(4):745-52. Int J Oncol. 2002. PMID: 11894120

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