Neuhaus P - Search Results

1

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation.

Bredschneider M, Klein K, Mürdter TE, Marx C, Eichelbaum M, Nüssler AK, Neuhaus P, Zanger UM, Schwab M. Bredschneider M, et al. Among authors: neuhaus p. Clin Pharmacol Ther. 2002 Jun;71(6):479-87. doi: 10.1067/mcp.2002.124518. Clin Pharmacol Ther. 2002. PMID: 12087351

2

The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.

Coller JK, Krebsfaenger N, Klein K, Endrizzi K, Wolbold R, Lang T, Nüssler A, Neuhaus P, Zanger UM, Eichelbaum M, Mürdter TE. Coller JK, et al. Among authors: neuhaus p. Br J Clin Pharmacol. 2002 Aug;54(2):157-67. doi: 10.1046/j.1365-2125.2002.01614.x. Br J Clin Pharmacol. 2002. PMID: 12207635 Free PMC article.

3

Influence of omeprazole on multidrug resistance protein 3 expression in human liver.

Hitzl M, Klein K, Zanger UM, Fritz P, Nüssler AK, Neuhaus P, Fromm MF. Hitzl M, et al. Among authors: neuhaus p. J Pharmacol Exp Ther. 2003 Feb;304(2):524-30. doi: 10.1124/jpet.102.043547. J Pharmacol Exp Ther. 2003. PMID: 12538803

4

Discriminative quantification of cytochrome P4502D6 and 2D7/8 pseudogene expression by TaqMan real-time reverse transcriptase polymerase chain reaction.

Endrizzi K, Fischer J, Klein K, Schwab M, Nüssler A, Neuhaus P, Eichelbaum M, Zanger UM. Endrizzi K, et al. Among authors: neuhaus p. Anal Biochem. 2002 Jan 15;300(2):121-31. doi: 10.1006/abio.2001.5453. Anal Biochem. 2002. PMID: 11779102

5

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. Burk O, et al. Among authors: neuhaus p. J Biol Chem. 2002 Jul 5;277(27):24280-8. doi: 10.1074/jbc.M202345200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940601 Free article.

6

Sex is a major determinant of CYP3A4 expression in human liver.

Wolbold R, Klein K, Burk O, Nüssler AK, Neuhaus P, Eichelbaum M, Schwab M, Zanger UM. Wolbold R, et al. Among authors: neuhaus p. Hepatology. 2003 Oct;38(4):978-88. doi: 10.1053/jhep.2003.50393. Hepatology. 2003. PMID: 14512885

7

Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity.

Coller JK, Krebsfaenger N, Klein K, Wolbold R, Nüssler A, Neuhaus P, Zanger UM, Eichelbaum M, Mürdter TE. Coller JK, et al. Among authors: neuhaus p. Br J Clin Pharmacol. 2004 Jan;57(1):105-11. doi: 10.1046/j.1365-2125.2003.01970.x. Br J Clin Pharmacol. 2004. PMID: 14678348 Free PMC article.

8

A naturally occurring mutation in the SLC21A6 gene causing impaired membrane localization of the hepatocyte uptake transporter.

Michalski C, Cui Y, Nies AT, Nuessler AK, Neuhaus P, Zanger UM, Klein K, Eichelbaum M, Keppler D, Konig J. Michalski C, et al. Among authors: neuhaus p. J Biol Chem. 2002 Nov 8;277(45):43058-63. doi: 10.1074/jbc.M207735200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196548 Free article.

9

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

Koch I, Weil R, Wolbold R, Brockmöller J, Hustert E, Burk O, Nuessler A, Neuhaus P, Eichelbaum M, Zanger U, Wojnowski L. Koch I, et al. Among authors: neuhaus p. Drug Metab Dispos. 2002 Oct;30(10):1108-14. doi: 10.1124/dmd.30.10.1108. Drug Metab Dispos. 2002. PMID: 12228187

10

Heme oxygenase-1 protects human hepatocytes in vitro against warm and cold hypoxia.

Tüzüner E, Liu L, Shimada M, Yilmaz E, Glanemann M, Settmacher U, Langrehr JM, Jonas S, Neuhaus P, Nussler AK. Tüzüner E, et al. Among authors: neuhaus p. J Hepatol. 2004 Nov;41(5):764-72. doi: 10.1016/j.jhep.2004.07.013. J Hepatol. 2004. PMID: 15519649

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