Willemsen RA - Search Results

1

TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity.

Chames P, Willemsen RA, Rojas G, Dieckmann D, Rem L, Schuler G, Bolhuis RL, Hoogenboom HR. Chames P, et al. Among authors: willemsen ra. J Immunol. 2002 Jul 15;169(2):1110-8. doi: 10.4049/jimmunol.169.2.1110. J Immunol. 2002. PMID: 12097420

2

Genetic engineering of T cell specificity for immunotherapy of cancer.

Willemsen RA, Debets R, Chames P, Bolhuis RL. Willemsen RA, et al. Hum Immunol. 2003 Jan;64(1):56-68. doi: 10.1016/s0198-8859(02)00730-9. Hum Immunol. 2003. PMID: 12507815 Review.

3

T cell retargeting with MHC class I-restricted antibodies: the CD28 costimulatory domain enhances antigen-specific cytotoxicity and cytokine production.

Willemsen RA, Ronteltap C, Chames P, Debets R, Bolhuis RL. Willemsen RA, et al. J Immunol. 2005 Jun 15;174(12):7853-8. doi: 10.4049/jimmunol.174.12.7853. J Immunol. 2005. PMID: 15944290 Free article.

4

Single chain Ig/gamma gene-redirected human T lymphocytes produce cytokines, specifically lyse tumor cells, and recycle lytic capacity.

Weijtens ME, Willemsen RA, Valerio D, Stam K, Bolhuis RL. Weijtens ME, et al. Among authors: willemsen ra. J Immunol. 1996 Jul 15;157(2):836-43. J Immunol. 1996. PMID: 8752936

5

Selection of human antibody fragments directed against tumor T-cell epitopes for adoptive T-cell therapy.

Willemsen R, Chames P, Schooten E, Gratama JW, Debets R. Willemsen R, et al. Cytometry A. 2008 Nov;73(11):1093-9. doi: 10.1002/cyto.a.20644. Cytometry A. 2008. PMID: 18785268 Free article. Review.

6

Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR.

Willemsen RA, Weijtens ME, Ronteltap C, Eshhar Z, Gratama JW, Chames P, Bolhuis RL. Willemsen RA, et al. Gene Ther. 2000 Aug;7(16):1369-77. doi: 10.1038/sj.gt.3301253. Gene Ther. 2000. PMID: 10981663

7

A phage display selected fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes.

Willemsen RA, Debets R, Hart E, Hoogenboom HR, Bolhuis RL, Chames P. Willemsen RA, et al. Gene Ther. 2001 Nov;8(21):1601-8. doi: 10.1038/sj.gt.3301570. Gene Ther. 2001. PMID: 11894998

8

Chimeric scFv/gamma receptor-mediated T-cell lysis of tumor cells is coregulated by adhesion and accessory molecules.

Weijtens ME, Willemsen RA, van Krimpen BA, Bolhuis RL. Weijtens ME, et al. Among authors: willemsen ra. Int J Cancer. 1998 Jul 17;77(2):181-7. doi: 10.1002/(sici)1097-0215(19980717)77:2<181::aid-ijc2>3.0.co;2-m. Int J Cancer. 1998. PMID: 9650549

9

A retroviral vector system 'STITCH' in combination with an optimized single chain antibody chimeric receptor gene structure allows efficient gene transduction and expression in human T lymphocytes.

Weijtens ME, Willemsen RA, Hart EH, Bolhuis RL. Weijtens ME, et al. Among authors: willemsen ra. Gene Ther. 1998 Sep;5(9):1195-203. doi: 10.1038/sj.gt.3300696. Gene Ther. 1998. PMID: 9930320

10

Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.

Stanislawski T, Voss RH, Lotz C, Sadovnikova E, Willemsen RA, Kuball J, Ruppert T, Bolhuis RL, Melief CJ, Huber C, Stauss HJ, Theobald M. Stanislawski T, et al. Among authors: willemsen ra. Nat Immunol. 2001 Oct;2(10):962-70. doi: 10.1038/ni1001-962. Nat Immunol. 2001. PMID: 11577350

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