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Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?
Paolini M, Abdel-Rahman SZ, Sapone A, Pedulli GF, Perocco P, Cantelli-Forti G, Legator MS. Paolini M, et al. Among authors: perocco p. Mutat Res. 2003 Jun;543(3):195-200. doi: 10.1016/s1383-5742(03)00002-4. Mutat Res. 2003. PMID: 12787812
Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli.
Paolini M, Perocco P, Canistro D, Valgimigli L, Pedulli GF, Iori R, Croce CD, Cantelli-Forti G, Legator MS, Abdel-Rahman SZ. Paolini M, et al. Among authors: perocco p. Carcinogenesis. 2004 Jan;25(1):61-7. doi: 10.1093/carcin/bgg174. Epub 2003 Sep 26. Carcinogenesis. 2004. PMID: 14514654
Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.
Perocco P, Bronzetti G, Canistro D, Valgimigli L, Sapone A, Affatato A, Pedulli GF, Pozzetti L, Broccoli M, Iori R, Barillari J, Sblendorio V, Legator MS, Paolini M, Abdel-Rahman SZ. Perocco P, et al. Mutat Res. 2006 Mar 20;595(1-2):125-36. doi: 10.1016/j.mrfmmm.2005.11.007. Mutat Res. 2006. PMID: 16442570
62 results