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Characterization of a novel radiolabeled peptide selective for a subpopulation of voltage-gated potassium channels in mammalian brain.
Racapé J, Lecoq A, Romi-Lebrun R, Liu J, Kohler M, Garcia ML, Ménez A, Gasparini S. Racapé J, et al. Among authors: menez a. J Biol Chem. 2002 Feb 8;277(6):3886-93. doi: 10.1074/jbc.M109886200. Epub 2001 Nov 13. J Biol Chem. 2002. PMID: 11707459 Free article.
BgK, a 37-amino acid voltage-gated potassium (Kv) 1 channel blocker isolated from the sea anemone Bunodosoma granulifera, can be modified at certain positions to alter its pharmacological profile (Alessandri-Haber, N., Lecoq, A., Gasparini, S., Grangier-Macmath, G., …
BgK, a 37-amino acid voltage-gated potassium (Kv) 1 channel blocker isolated from the sea anemone Bunodosoma granulifera, can be modi …
A variable residue in the pore of Kv1 channels is critical for the high affinity of blockers from sea anemones and scorpions.
Gilquin B, Braud S, Eriksson MA, Roux B, Bailey TD, Priest BT, Garcia ML, Ménez A, Gasparini S. Gilquin B, et al. Among authors: menez a. J Biol Chem. 2005 Jul 22;280(29):27093-102. doi: 10.1074/jbc.M413626200. Epub 2005 May 12. J Biol Chem. 2005. PMID: 15890656 Free article.
To address this issue we refined our previous three-dimensional models of the complex between the sea anemone toxin BgK and the S5-S6 region of Kv1.1 (Gilquin, B., Racape, J., Wrisch, A., Visan, V., Lecoq, A., Grissmer, S., Menez, A., and Gasparini, S. …
To address this issue we refined our previous three-dimensional models of the complex between the sea anemone toxin BgK and the S5-S6 region …
Delineation of the functional site of alpha-dendrotoxin. The functional topographies of dendrotoxins are different but share a conserved core with those of other Kv1 potassium channel-blocking toxins.
Gasparini S, Danse JM, Lecoq A, Pinkasfeld S, Zinn-Justin S, Young LC, de Medeiros CC, Rowan EG, Harvey AL, Ménez A. Gasparini S, et al. Among authors: menez a. J Biol Chem. 1998 Sep 25;273(39):25393-403. doi: 10.1074/jbc.273.39.25393. J Biol Chem. 1998. PMID: 9738007 Free article.
Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor.
Marquer C, Fruchart-Gaillard C, Letellier G, Marcon E, Mourier G, Zinn-Justin S, Ménez A, Servent D, Gilquin B. Marquer C, et al. Among authors: menez a. J Biol Chem. 2011 Sep 9;286(36):31661-75. doi: 10.1074/jbc.M111.261404. Epub 2011 Jun 17. J Biol Chem. 2011. PMID: 21685390 Free PMC article.
254 results