Takanaga H - Search Results

1

Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates.

Tian R, Koyabu N, Takanaga H, Matsuo H, Ohtani H, Sawada Y. Tian R, et al. Among authors: takanaga h. Pharm Res. 2002 Jun;19(6):802-9. doi: 10.1023/a:1016100715125. Pharm Res. 2002. PMID: 12134950

2

Contribution of P-glycoprotein to efflux of ramosetron, a 5-HT3 receptor antagonist, across the blood-brain barrier.

Yamamoto C, Murakami H, Koyabu N, Takanaga H, Matsuo H, Uchiumi T, Kuwano M, Naito M, Tsuruo T, Ohtani H, Sawada Y. Yamamoto C, et al. Among authors: takanaga h. J Pharm Pharmacol. 2002 Aug;54(8):1055-63. doi: 10.1211/002235702320266208. J Pharm Pharmacol. 2002. PMID: 12195819

3

Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells.

Takanaga H, Ohnishi A, Matsuo H, Sawada Y. Takanaga H, et al. Biol Pharm Bull. 1998 Oct;21(10):1062-6. doi: 10.1248/bpb.21.1062. Biol Pharm Bull. 1998. PMID: 9821810 Free article.

4

Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4.

Takanaga H, Ohnishi A, Yamada S, Matsuo H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Takanaga H, et al. J Pharmacol Exp Ther. 2000 Apr;293(1):230-6. J Pharmacol Exp Ther. 2000. PMID: 10734174

5

Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.

Ohnishi A, Matsuo H, Yamada S, Takanaga H, Morimoto S, Shoyama Y, Ohtani H, Sawada Y. Ohnishi A, et al. Among authors: takanaga h. Br J Pharmacol. 2000 Jul;130(6):1369-77. doi: 10.1038/sj.bjp.0703433. Br J Pharmacol. 2000. PMID: 10903978 Free PMC article.

6

Possibility of the reversal of multidrug resistance and the avoidance of side effects by liposomes modified with MRK-16, a monoclonal antibody to P-glycoprotein.

Matsuo H, Wakasugi M, Takanaga H, Ohtani H, Naito M, Tsuruo T, Sawada Y. Matsuo H, et al. Among authors: takanaga h. J Control Release. 2001 Nov 9;77(1-2):77-86. doi: 10.1016/s0168-3659(01)00460-6. J Control Release. 2001. PMID: 11689261

7

Tolbutamide uptake via pH- and membrane-potential-dependent transport mechanism in mouse brain capillary endothelial cell line.

Koyabu N, Takanaga H, Matsuo H, Naito M, Tsuruo T, Ohtani H, Sawada Y. Koyabu N, et al. Among authors: takanaga h. Drug Metab Pharmacokinet. 2004 Aug;19(4):270-9. doi: 10.2133/dmpk.19.270. Drug Metab Pharmacokinet. 2004. PMID: 15499195 Free article.

8

Functional characterization of adenosine transport across the BBB in mice.

Murakami H, Ohkura A, Takanaga H, Matsuo H, Koyabu N, Naito M, Tsuruo T, Ohtani H, Sawada Y. Murakami H, et al. Among authors: takanaga h. Int J Pharm. 2005 Feb 16;290(1-2):37-44. doi: 10.1016/j.ijpharm.2004.11.005. Epub 2005 Jan 4. Int J Pharm. 2005. PMID: 15664128

9

Efflux transport of tolbutamide across the blood-brain barrier.

Takanaga H, Murakami H, Koyabu N, Matsuo H, Naito M, Tsuruo T, Sawada Y. Takanaga H, et al. J Pharm Pharmacol. 1998 Sep;50(9):1027-33. doi: 10.1111/j.2042-7158.1998.tb06918.x. J Pharm Pharmacol. 1998. PMID: 9811164

10

Contribution of P-glycoprotein to bunitrolol efflux across blood-brain barrier.

Matsuzaki J, Yamamoto C, Miyama T, Takanaga H, Matsuo H, Ishizuka H, Kawahara Y, Kuwano M, Naito M, Tsuruo T, Sawada Y. Matsuzaki J, et al. Among authors: takanaga h. Biopharm Drug Dispos. 1999 Mar;20(2):85-90. doi: 10.1002/(sici)1099-081x(199903)20:2<85::aid-bdd159>3.0.co;2-3. Biopharm Drug Dispos. 1999. PMID: 10206323

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