Hume SP - Search Results

1

Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography.

Lingford-Hughes A, Hume SP, Feeney A, Hirani E, Osman S, Cunningham VJ, Pike VW, Brooks DJ, Nutt DJ. Lingford-Hughes A, et al. Among authors: hume sp. J Cereb Blood Flow Metab. 2002 Jul;22(7):878-89. doi: 10.1097/00004647-200207000-00013. J Cereb Blood Flow Metab. 2002. PMID: 12142573

2

Comparison of methods for analysis of clinical [11C]raclopride studies.

Lammertsma AA, Bench CJ, Hume SP, Osman S, Gunn K, Brooks DJ, Frackowiak RS. Lammertsma AA, et al. Among authors: hume sp. J Cereb Blood Flow Metab. 1996 Jan;16(1):42-52. doi: 10.1097/00004647-199601000-00005. J Cereb Blood Flow Metab. 1996. PMID: 8530554

3

Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central alpha2-adrenoceptors.

Hume SP, Hirani E, Opacka-Juffry J, Osman S, Myers R, Gunn RN, McCarron JA, Clark RD, Melichar J, Nutt DJ, Pike VW. Hume SP, et al. Eur J Nucl Med. 2000 May;27(5):475-84. doi: 10.1007/s002590050531. Eur J Nucl Med. 2000. PMID: 10853800 Clinical Trial.

4

Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET.

Pike VW, Halldin C, Nobuhara K, Hiltunen J, Mulligan RS, Swahn CG, Karlsson P, Olsson H, Hume SP, Hirani E, Whalley J, Pilowsky LS, Larsson S, Schnell PO, Ell PJ, Farde L. Pike VW, et al. Among authors: hume sp. Eur J Nucl Med Mol Imaging. 2003 Nov;30(11):1520-8. doi: 10.1007/s00259-003-1307-x. Epub 2003 Sep 23. Eur J Nucl Med Mol Imaging. 2003. PMID: 14579092

5

Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies.

Melichar JK, Hume SP, Williams TM, Daglish MR, Taylor LG, Ahmad R, Malizia AL, Brooks DJ, Myles JS, Lingford-Hughes A, Nutt DJ. Melichar JK, et al. Among authors: hume sp. J Pharmacol Exp Ther. 2005 Jan;312(1):309-15. doi: 10.1124/jpet.104.072686. Epub 2004 Sep 3. J Pharmacol Exp Ther. 2005. PMID: 15347732

6

Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002.

Tyacke RJ, Robinson ES, Lalies MD, Hume SP, Hudson AL, Nutt DJ. Tyacke RJ, et al. Among authors: hume sp. Synapse. 2005 Feb;55(2):126-32. doi: 10.1002/syn.20100. Synapse. 2005. PMID: 15543627

7

Effect of reduction in endogenous dopamine on extrastriatal binding of [11C]FLB 457 in rat brain--an ex vivo study.

Ahmad R, Hirani E, Grasby PM, Hume SP. Ahmad R, et al. Among authors: hume sp. Synapse. 2006 Mar 1;59(3):162-72. doi: 10.1002/syn.20231. Synapse. 2006. PMID: 16358331

8

Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opiates.

Hume SP, Lingford-Hughes AR, Nataf V, Hirani E, Ahmad R, Davies AN, Nutt DJ. Hume SP, et al. J Pharmacol Exp Ther. 2007 Aug;322(2):661-7. doi: 10.1124/jpet.107.121749. Epub 2007 May 8. J Pharmacol Exp Ther. 2007. PMID: 17488881

9

Positron emission tomography analysis of [11C]KW-6002 binding to human and rat adenosine A2A receptors in the brain.

Brooks DJ, Doder M, Osman S, Luthra SK, Hirani E, Hume S, Kase H, Kilborn J, Martindill S, Mori A. Brooks DJ, et al. Synapse. 2008 Sep;62(9):671-81. doi: 10.1002/syn.20539. Synapse. 2008. PMID: 18566974 Clinical Trial.

10

[carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.

Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L. Pike VW, et al. Among authors: hume sp. Eur J Nucl Med. 1998 Apr;25(4):338-46. doi: 10.1007/s002590050230. Eur J Nucl Med. 1998. PMID: 9553162

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