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Page 1
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.
Duffy KJ, Shaw AN, Delorme E, Dillon SB, Erickson-Miller C, Giampa L, Huang Y, Keenan RM, Lamb P, Liu N, Miller SG, Price AT, Rosen J, Smith H, Wiggall KJ, Zhang L, Luengo JI. Duffy KJ, et al. Among authors: giampa l. J Med Chem. 2002 Aug 15;45(17):3573-5. doi: 10.1021/jm025535c. J Med Chem. 2002. PMID: 12166928
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics.
Duffy KJ, Price AT, Delorme E, Dillon SB, Duquenne C, Erickson-Miller C, Giampa L, Huang Y, Keenan RM, Lamb P, Liu N, Miller SG, Rosen J, Shaw AN, Smith H, Wiggall KJ, Zhang L, Luengo JI. Duffy KJ, et al. Among authors: giampa l. J Med Chem. 2002 Aug 15;45(17):3576-8. doi: 10.1021/jm0255365. J Med Chem. 2002. PMID: 12166929
Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.
Duffy KJ, Darcy MG, Delorme E, Dillon SB, Eppley DF, Erickson-Miller C, Giampa L, Hopson CB, Huang Y, Keenan RM, Lamb P, Leong L, Liu N, Miller SG, Price AT, Rosen J, Shah R, Shaw TN, Smith H, Stark KC, Tian SS, Tyree C, Wiggall KJ, Zhang L, Luengo JI. Duffy KJ, et al. Among authors: giampa l. J Med Chem. 2001 Oct 25;44(22):3730-45. doi: 10.1021/jm010283l. J Med Chem. 2001. PMID: 11606138
Vav: function and regulation in hematopoietic cell signaling.
Bonnefoy-Bérard N, Munshi A, Yron I, Wu S, Collins TL, Deckert M, Shalom-Barak T, Giampa L, Herbert E, Hernandez J, Meller N, Couture C, Altman A. Bonnefoy-Bérard N, et al. Among authors: giampa l. Stem Cells. 1996 May;14(3):250-68. doi: 10.1002/stem.140250. Stem Cells. 1996. PMID: 8724692 Review.
12 results