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Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 2. Rational design of naphtho[1,2-d]imidazole thrombopoietin mimics.
Duffy KJ, Price AT, Delorme E, Dillon SB, Duquenne C, Erickson-Miller C, Giampa L, Huang Y, Keenan RM, Lamb P, Liu N, Miller SG, Rosen J, Shaw AN, Smith H, Wiggall KJ, Zhang L, Luengo JI. Duffy KJ, et al. Among authors: zhang l. J Med Chem. 2002 Aug 15;45(17):3576-8. doi: 10.1021/jm0255365. J Med Chem. 2002. PMID: 12166929
Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone thrombopoietin mimics.
Duffy KJ, Shaw AN, Delorme E, Dillon SB, Erickson-Miller C, Giampa L, Huang Y, Keenan RM, Lamb P, Liu N, Miller SG, Price AT, Rosen J, Smith H, Wiggall KJ, Zhang L, Luengo JI. Duffy KJ, et al. Among authors: zhang l. J Med Chem. 2002 Aug 15;45(17):3573-5. doi: 10.1021/jm025535c. J Med Chem. 2002. PMID: 12166928
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