Alessi DR - Search Results

1

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate.

Thomas CC, Deak M, Alessi DR, van Aalten DM. Thomas CC, et al. Among authors: alessi dr. Curr Biol. 2002 Jul 23;12(14):1256-62. doi: 10.1016/s0960-9822(02)00972-7. Curr Biol. 2002. PMID: 12176338 Free article.

2

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

James SR, Downes CP, Gigg R, Grove SJ, Holmes AB, Alessi DR. James SR, et al. Among authors: alessi dr. Biochem J. 1996 May 1;315 ( Pt 3)(Pt 3):709-13. doi: 10.1042/bj3150709. Biochem J. 1996. PMID: 8645147 Free PMC article.

3

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.

Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB, Cohen P. Alessi DR, et al. Curr Biol. 1997 Apr 1;7(4):261-9. doi: 10.1016/s0960-9822(06)00122-9. Curr Biol. 1997. PMID: 9094314 Free article.

4

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M. Alessi DR, et al. Curr Biol. 1997 Oct 1;7(10):776-89. doi: 10.1016/s0960-9822(06)00336-8. Curr Biol. 1997. PMID: 9368760 Free article.

5

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.

Alessi DR, Kozlowski MT, Weng QP, Morrice N, Avruch J. Alessi DR, et al. Curr Biol. 1998 Jan 15;8(2):69-81. doi: 10.1016/s0960-9822(98)70037-5. Curr Biol. 1998. PMID: 9427642 Free article.

6

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

7

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

Deak M, Clifton AD, Lucocq LM, Alessi DR. Deak M, et al. Among authors: alessi dr. EMBO J. 1998 Aug 3;17(15):4426-41. doi: 10.1093/emboj/17.15.4426. EMBO J. 1998. PMID: 9687510 Free PMC article.

8

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

9

Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast.

Casamayor A, Torrance PD, Kobayashi T, Thorner J, Alessi DR. Casamayor A, et al. Among authors: alessi dr. Curr Biol. 1999 Feb 25;9(4):186-97. doi: 10.1016/s0960-9822(99)80088-8. Curr Biol. 1999. PMID: 10074427 Free article.

10

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

Balendran A, Casamayor A, Deak M, Paterson A, Gaffney P, Currie R, Downes CP, Alessi DR. Balendran A, et al. Among authors: alessi dr. Curr Biol. 1999 Apr 22;9(8):393-404. doi: 10.1016/s0960-9822(99)80186-9. Curr Biol. 1999. PMID: 10226025 Free article.

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