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Page 1
Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma.
Kim ES, Serur A, Huang J, Manley CA, McCrudden KW, Frischer JS, Soffer SZ, Ring L, New T, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. Kim ES, et al. Among authors: rudge js. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11399-404. doi: 10.1073/pnas.172398399. Epub 2002 Aug 12. Proc Natl Acad Sci U S A. 2002. PMID: 12177446 Free PMC article.
VEGF-Trap: a VEGF blocker with potent antitumor effects.
Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E, Huang T, Radziejewski C, Bailey K, Fandl JP, Daly T, Wiegand SJ, Yancopoulos GD, Rudge JS. Holash J, et al. Among authors: rudge js. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11393-8. doi: 10.1073/pnas.172398299. Epub 2002 Aug 12. Proc Natl Acad Sci U S A. 2002. PMID: 12177445 Free PMC article.
Regression of established tumors and metastases by potent vascular endothelial growth factor blockade.
Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O'Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Huang J, et al. Among authors: rudge js. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7785-90. doi: 10.1073/pnas.1432908100. Epub 2003 Jun 12. Proc Natl Acad Sci U S A. 2003. PMID: 12805568 Free PMC article.
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade.
Rudge JS, Holash J, Hylton D, Russell M, Jiang S, Leidich R, Papadopoulos N, Pyles EA, Torri A, Wiegand SJ, Thurston G, Stahl N, Yancopoulos GD. Rudge JS, et al. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18363-70. doi: 10.1073/pnas.0708865104. Epub 2007 Nov 13. Proc Natl Acad Sci U S A. 2007. PMID: 18000042 Free PMC article.
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells.
Daly C, Pasnikowski E, Burova E, Wong V, Aldrich TH, Griffiths J, Ioffe E, Daly TJ, Fandl JP, Papadopoulos N, McDonald DM, Thurston G, Yancopoulos GD, Rudge JS. Daly C, et al. Among authors: rudge js. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15491-6. doi: 10.1073/pnas.0607538103. Epub 2006 Oct 9. Proc Natl Acad Sci U S A. 2006. PMID: 17030814 Free PMC article.
67 results