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Page 1
8-Aryl xanthines potent inhibitors of phosphodiesterase 5.
Arnold R, Beer D, Bhalay G, Baettig U, Collingwood SP, Craig S, Devereux N, Dunstan A, Glen A, Gomez S, Haberthuer S, Howe T, Jelfs S, Moser H, Naef R, Nicklin P, Sandham D, Stringer R, Turner K, Watson S, Zurini M. Arnold R, et al. Among authors: naef r. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2587-90. doi: 10.1016/s0960-894x(02)00480-8. Bioorg Med Chem Lett. 2002. PMID: 12182866
Potent and selective xanthine-based inhibitors of phosphodiesterase 5.
Arnold NJ, Arnold R, Beer D, Bhalay G, Collingwood SP, Craig S, Devereux N, Dodds M, Dunstan AR, Fairhurst RA, Farr D, Fullerton JD, Glen A, Gomez S, Haberthuer S, Hatto JD, Howes C, Jones D, Keller TH, Leuenberger B, Moser HE, Muller I, Naef R, Nicklin PA, Sandham DA, Turner KL, Tweed MF, Watson SJ, Zurini M. Arnold NJ, et al. Among authors: naef r. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2376-9. doi: 10.1016/j.bmcl.2006.11.019. Epub 2006 Nov 10. Bioorg Med Chem Lett. 2007. PMID: 17337182
Quinazolines: combined type 3 and 4 phosphodiesterase inhibitors.
Charpiot B, Brun J, Donze I, Naef R, Stefani M, Mueller T. Charpiot B, et al. Among authors: naef r. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2891-6. doi: 10.1016/s0960-894x(98)00508-3. Bioorg Med Chem Lett. 1998. PMID: 9873643
Disease activated drugs: a new concept for the treatment of asthma.
Charpiot B, Bitsch F, Buchheit KH, Channez P, Mazzoni L, Mueller T, Vachier I, Naef R. Charpiot B, et al. Among authors: naef r. Bioorg Med Chem. 2001 Jul;9(7):1793-805. doi: 10.1016/s0968-0896(01)00077-3. Bioorg Med Chem. 2001. PMID: 11425581
136 results