Altman A - Search Results

1

Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias.

Villalba M, Altman A. Villalba M, et al. Among authors: altman a. Curr Cancer Drug Targets. 2002 Jun;2(2):125-37. doi: 10.2174/1568009023333908. Curr Cancer Drug Targets. 2002. PMID: 12188914 Review.

2

Positive feedback regulation of PLCgamma1/Ca(2+) signaling by PKCtheta in restimulated T cells via a Tec kinase-dependent pathway.

Altman A, Kaminski S, Busuttil V, Droin N, Hu J, Tadevosyan Y, Hipskind RA, Villalba M. Altman A, et al. Eur J Immunol. 2004 Jul;34(7):2001-11. doi: 10.1002/eji.200324625. Eur J Immunol. 2004. PMID: 15214048 Free article.

3

Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death.

Altman A, Villalba M. Altman A, et al. J Biochem. 2002 Dec;132(6):841-6. doi: 10.1093/oxfordjournals.jbchem.a003295. J Biochem. 2002. PMID: 12473184 Free article. Review.

4

Protein kinase C-theta (PKCtheta): it's all about location, location, location.

Altman A, Villalba M. Altman A, et al. Immunol Rev. 2003 Apr;192:53-63. doi: 10.1034/j.1600-065x.2003.00027.x. Immunol Rev. 2003. PMID: 12670395 Review.

5

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A. Villalba M, et al. Among authors: altman a, altman y. J Cell Biol. 2002 Apr 15;157(2):253-63. doi: 10.1083/jcb.200201097. Epub 2002 Apr 15. J Cell Biol. 2002. PMID: 11956228 Free PMC article.

6

Protein kinase ctheta cooperates with calcineurin to induce Fas ligand expression during activation-induced T cell death.

Villalba M, Kasibhatla S, Genestier L, Mahboubi A, Green DR, Altman A. Villalba M, et al. Among authors: altman a. J Immunol. 1999 Dec 1;163(11):5813-9. J Immunol. 1999. PMID: 10570264

7

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

Villalba M, Coudronniere N, Deckert M, Teixeiro E, Mas P, Altman A. Villalba M, et al. Among authors: altman a. Immunity. 2000 Feb;12(2):151-60. doi: 10.1016/s1074-7613(00)80168-5. Immunity. 2000. PMID: 10714681 Free article.

8

NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta.

Coudronniere N, Villalba M, Englund N, Altman A. Coudronniere N, et al. Among authors: altman a. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3394-9. doi: 10.1073/pnas.97.7.3394. Proc Natl Acad Sci U S A. 2000. PMID: 10716728 Free PMC article.

9

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD.

Villalba M, Bushway P, Altman A. Villalba M, et al. Among authors: altman a. J Immunol. 2001 May 15;166(10):5955-63. doi: 10.4049/jimmunol.166.10.5955. J Immunol. 2001. PMID: 11342610

10

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading.

del Pozo MA, Schwartz MA, Hu J, Kiosses WB, Altman A, Villalba M. del Pozo MA, et al. Among authors: altman a. J Immunol. 2003 Jan 1;170(1):41-7. doi: 10.4049/jimmunol.170.1.41. J Immunol. 2003. PMID: 12496381

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