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Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway.
Irukayama-Tomobe Y, Miyauchi T, Sakai S, Kasuya Y, Ogata T, Takanashi M, Iemitsu M, Sudo T, Goto K, Yamaguchi I. Irukayama-Tomobe Y, et al. Among authors: ogata t. Circulation. 2004 Feb 24;109(7):904-10. doi: 10.1161/01.CIR.0000112596.06954.00. Epub 2004 Feb 16. Circulation. 2004. PMID: 14967736
Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-B pathway.
Ogata T, Miyauchi T, Sakai S, Takanashi M, Irukayama-Tomobe Y, Yamaguchi I. Ogata T, et al. J Am Coll Cardiol. 2004 Apr 21;43(8):1481-8. doi: 10.1016/j.jacc.2003.11.043. J Am Coll Cardiol. 2004. PMID: 15093887 Free article.
Effects of endothelin-1 eyedrops on the retina in rats.
Masuzawa K, Miyauchi T, Takanashi M, Ogata T, Yamaguchi I, Goto K. Masuzawa K, et al. Among authors: ogata t. J Cardiovasc Pharmacol. 2004 Nov;44 Suppl 1:S421-5. doi: 10.1097/01.fjc.0000166286.85785.a1. J Cardiovasc Pharmacol. 2004. PMID: 15838338
2,111 results