Derrick S - Search Results

1

A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

Sambandamurthy VK, Wang X, Chen B, Russell RG, Derrick S, Collins FM, Morris SL, Jacobs WR Jr. Sambandamurthy VK, et al. Among authors: derrick s. Nat Med. 2002 Oct;8(10):1171-4. doi: 10.1038/nm765. Epub 2002 Sep 9. Nat Med. 2002. PMID: 12219086

2

The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue.

Hsu T, Hingley-Wilson SM, Chen B, Chen M, Dai AZ, Morin PM, Marks CB, Padiyar J, Goulding C, Gingery M, Eisenberg D, Russell RG, Derrick SC, Collins FM, Morris SL, King CH, Jacobs WR Jr. Hsu T, et al. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12420-5. doi: 10.1073/pnas.1635213100. Epub 2003 Oct 13. Proc Natl Acad Sci U S A. 2003. PMID: 14557547 Free PMC article.

3

Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis.

Sambandamurthy VK, Derrick SC, Jalapathy KV, Chen B, Russell RG, Morris SL, Jacobs WR Jr. Sambandamurthy VK, et al. Infect Immun. 2005 Feb;73(2):1196-203. doi: 10.1128/IAI.73.2.1196-1203.2005. Infect Immun. 2005. PMID: 15664964 Free PMC article.

4

Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.

Sambandamurthy VK, Derrick SC, Hsu T, Chen B, Larsen MH, Jalapathy KV, Chen M, Kim J, Porcelli SA, Chan J, Morris SL, Jacobs WR Jr. Sambandamurthy VK, et al. Vaccine. 2006 Sep 11;24(37-39):6309-20. doi: 10.1016/j.vaccine.2006.05.097. Epub 2006 Jun 12. Vaccine. 2006. PMID: 16860907

5

Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.

Hinchey J, Lee S, Jeon BY, Basaraba RJ, Venkataswamy MM, Chen B, Chan J, Braunstein M, Orme IM, Derrick SC, Morris SL, Jacobs WR Jr, Porcelli SA. Hinchey J, et al. Among authors: derrick sc. J Clin Invest. 2007 Aug;117(8):2279-88. doi: 10.1172/JCI31947. J Clin Invest. 2007. PMID: 17671656 Free PMC article.

6

Lysine auxotrophy combined with deletion of the SecA2 gene results in a safe and highly immunogenic candidate live attenuated vaccine for tuberculosis.

Hinchey J, Jeon BY, Alley H, Chen B, Goldberg M, Derrick S, Morris S, Jacobs WR Jr, Porcelli SA, Lee S. Hinchey J, et al. Among authors: derrick s. PLoS One. 2011 Jan 10;6(1):e15857. doi: 10.1371/journal.pone.0015857. PLoS One. 2011. PMID: 21264335 Free PMC article.

7

Immunization with a DNA vaccine cocktail protects mice lacking CD4 cells against an aerogenic infection with Mycobacterium tuberculosis.

Derrick SC, Repique C, Snoy P, Yang AL, Morris S. Derrick SC, et al. Infect Immun. 2004 Mar;72(3):1685-92. doi: 10.1128/IAI.72.3.1685-1692.2004. Infect Immun. 2004. PMID: 14977976 Free PMC article.

8

A polyvalent DNA vaccine expressing an ESAT6-Ag85B fusion protein protects mice against a primary infection with Mycobacterium tuberculosis and boosts BCG-induced protective immunity.

Derrick SC, Yang AL, Morris SL. Derrick SC, et al. Vaccine. 2004 Dec 21;23(6):780-8. doi: 10.1016/j.vaccine.2004.07.036. Vaccine. 2004. PMID: 15542202

9

Vaccination with a Sindbis virus-based DNA vaccine expressing antigen 85B induces protective immunity against Mycobacterium tuberculosis.

Derrick SC, Yang AL, Morris SL. Derrick SC, et al. Infect Immun. 2005 Nov;73(11):7727-35. doi: 10.1128/IAI.73.11.7727-7735.2005. Infect Immun. 2005. PMID: 16239577 Free PMC article.

10

Protection against an aerogenic Mycobacterium tuberculosis infection in BCG-immunized and DNA-vaccinated mice is associated with early type I cytokine responses.

Goter-Robinson C, Derrick SC, Yang AL, Jeon BY, Morris SL. Goter-Robinson C, et al. Vaccine. 2006 Apr 24;24(17):3522-9. doi: 10.1016/j.vaccine.2006.02.005. Epub 2006 Feb 20. Vaccine. 2006. PMID: 16519971

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