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Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Rajagopalan S, Rourke AK, Asare E, Kohlerschmidt DJ, Das L, Ngema SL, Mulholland CV, Vilchèze C, Mahalingam V, Moodley S, Truebody B, Mackenzie J, Steyn AJC, Perumal R, Berney M, Larsen MH, O'Donnell MR, Escuyer VE, Jacobs WR Jr. Rajagopalan S, et al. Among authors: jacobs wr jr. J Infect Dis. 2024 Oct 16:jiae438. doi: 10.1093/infdis/jiae438. Online ahead of print. J Infect Dis. 2024. PMID: 39412357
Propionate prevents loss of the PDIM virulence lipid in Mycobacterium tuberculosis.
Mulholland CV, Wiggins TJ, Cui J, Vilchèze C, Rajagopalan S, Shultis MW, Reyes-Fernández EZ, Jacobs WR Jr, Berney M. Mulholland CV, et al. Among authors: jacobs wr jr. Nat Microbiol. 2024 Jun;9(6):1607-1618. doi: 10.1038/s41564-024-01697-8. Epub 2024 May 13. Nat Microbiol. 2024. PMID: 38740932 Free PMC article.
Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis.
Pandey S, Vilchèze C, Werngren J, Bainomugisa A, Mansjö M, Groenheit R, Miotto P, Cirillo DM, Coulter C, Baulard AR, Schön T, Jacobs WR Jr, Djaout K, Köser CU. Pandey S, et al. Among authors: jacobs wr jr. Antimicrob Agents Chemother. 2024 Jan 10;68(1):e0109623. doi: 10.1128/aac.01096-23. Epub 2023 Dec 1. Antimicrob Agents Chemother. 2024. PMID: 38038476 Free PMC article.
The PDIM paradox of Mycobacterium tuberculosis: new solutions to a persistent problem.
Mulholland CV, Wiggins TJ, Cui J, Vilchèze C, Rajagopalan S, Shultis MW, Reyes-Fernández EZ, Jacobs WR Jr, Berney M. Mulholland CV, et al. Among authors: jacobs wr jr. bioRxiv [Preprint]. 2023 Oct 16:2023.10.16.562559. doi: 10.1101/2023.10.16.562559. bioRxiv. 2023. Update in: Nat Microbiol. 2024 Jun;9(6):1607-1618. doi: 10.1038/s41564-024-01697-8 PMID: 37905120 Free PMC article. Updated. Preprint.
387 results