Martinez J - Search Results

1

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.

Martinez J, Patkaniowska A, Urlaub H, Lührmann R, Tuschl T. Martinez J, et al. Cell. 2002 Sep 6;110(5):563-74. doi: 10.1016/s0092-8674(02)00908-x. Cell. 2002. PMID: 12230974 Free article.

2

RISC is a 5' phosphomonoester-producing RNA endonuclease.

Martinez J, Tuschl T. Martinez J, et al. Genes Dev. 2004 May 1;18(9):975-80. doi: 10.1101/gad.1187904. Epub 2004 Apr 22. Genes Dev. 2004. PMID: 15105377 Free PMC article.

3

Molecular basis for target RNA recognition and cleavage by human RISC.

Ameres SL, Martinez J, Schroeder R. Ameres SL, et al. Among authors: martinez j. Cell. 2007 Jul 13;130(1):101-12. doi: 10.1016/j.cell.2007.04.037. Cell. 2007. PMID: 17632058 Free article.

4

Analysis of mammalian gene function using small interfering RNAs.

Martinez J, Patkaniowska A, Elbashir SM, Harborth J, Hossbach M, Urlaub H, Meyer J, Weber K, Vandenburgh K, Manninga H, Scaringe SA, Luehrmann R, Tuschl T. Martinez J, et al. Nucleic Acids Res Suppl. 2003;(3):333. doi: 10.1093/nass/3.1.333. Nucleic Acids Res Suppl. 2003. PMID: 14510516 No abstract available.

5

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.

Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M; Baylor Hopkins Center for Mendelian Genomics; Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR. Karaca E, et al. Among authors: martinez j. Cell. 2014 Apr 24;157(3):636-50. doi: 10.1016/j.cell.2014.02.058. Cell. 2014. PMID: 24766809 Free PMC article.

6

The impact of target site accessibility on the design of effective siRNAs.

Tafer H, Ameres SL, Obernosterer G, Gebeshuber CA, Schroeder R, Martinez J, Hofacker IL. Tafer H, et al. Among authors: martinez j. Nat Biotechnol. 2008 May;26(5):578-83. doi: 10.1038/nbt1404. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438400

7

HSPC117 is the essential subunit of a human tRNA splicing ligase complex.

Popow J, Englert M, Weitzer S, Schleiffer A, Mierzwa B, Mechtler K, Trowitzsch S, Will CL, Lührmann R, Söll D, Martinez J. Popow J, et al. Among authors: martinez j. Science. 2011 Feb 11;331(6018):760-4. doi: 10.1126/science.1197847. Science. 2011. PMID: 21311021

8

Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.

Sekulovski S, Devant P, Panizza S, Gogakos T, Pitiriciu A, Heitmeier K, Ramsay EP, Barth M, Schmidt C, Tuschl T, Baas F, Weitzer S, Martinez J, Trowitzsch S. Sekulovski S, et al. Among authors: martinez j. Nat Commun. 2021 Sep 28;12(1):5610. doi: 10.1038/s41467-021-25870-3. Nat Commun. 2021. PMID: 34584079 Free PMC article.

9

hClp1: a novel kinase revitalizes RNA metabolism.

Weitzer S, Martinez J. Weitzer S, et al. Among authors: martinez j. Cell Cycle. 2007 Sep 1;6(17):2133-7. doi: 10.4161/cc.6.17.4642. Epub 2007 Jun 27. Cell Cycle. 2007. PMID: 17786051

10

Cleavage of the siRNA passenger strand during RISC assembly in human cells.

Leuschner PJ, Ameres SL, Kueng S, Martinez J. Leuschner PJ, et al. Among authors: martinez j. EMBO Rep. 2006 Mar;7(3):314-20. doi: 10.1038/sj.embor.7400637. Epub 2006 Jan 20. EMBO Rep. 2006. PMID: 16439995 Free PMC article.

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