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Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.
Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM. Crackower MA, et al. Among authors: shioi t. Cell. 2002 Sep 20;110(6):737-49. doi: 10.1016/s0092-8674(02)00969-8. Cell. 2002. PMID: 12297047 Free article.
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. O'Neill BT, et al. Among authors: shioi t. Cell Metab. 2007 Oct;6(4):294-306. doi: 10.1016/j.cmet.2007.09.001. Cell Metab. 2007. PMID: 17908558 Free PMC article.
Akt/protein kinase B promotes organ growth in transgenic mice.
Shioi T, McMullen JR, Kang PM, Douglas PS, Obata T, Franke TF, Cantley LC, Izumo S. Shioi T, et al. Mol Cell Biol. 2002 Apr;22(8):2799-809. doi: 10.1128/MCB.22.8.2799-2809.2002. Mol Cell Biol. 2002. PMID: 11909972 Free PMC article.
Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.
Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM. Rigor DL, et al. Among authors: shioi t. Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H566-72. doi: 10.1152/ajpheart.00562.2008. Epub 2009 Jan 2. Am J Physiol Heart Circ Physiol. 2009. PMID: 19122165 Free PMC article.
Rapamycin attenuates load-induced cardiac hypertrophy in mice.
Shioi T, McMullen JR, Tarnavski O, Converso K, Sherwood MC, Manning WJ, Izumo S. Shioi T, et al. Circulation. 2003 Apr 1;107(12):1664-70. doi: 10.1161/01.CIR.0000057979.36322.88. Epub 2003 Mar 17. Circulation. 2003. PMID: 12668503
82 results