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Page 1
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.
Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM. Crackower MA, et al. Among authors: wymann mp. Cell. 2002 Sep 20;110(6):737-49. doi: 10.1016/s0092-8674(02)00969-8. Cell. 2002. PMID: 12297047 Free article.
Integrating cardiac PIP3 and cAMP signaling through a PKA anchoring function of p110γ.
Perino A, Ghigo A, Ferrero E, Morello F, Santulli G, Baillie GS, Damilano F, Dunlop AJ, Pawson C, Walser R, Levi R, Altruda F, Silengo L, Langeberg LK, Neubauer G, Heymans S, Lembo G, Wymann MP, Wetzker R, Houslay MD, Iaccarino G, Scott JD, Hirsch E. Perino A, et al. Among authors: wymann mp. Mol Cell. 2011 Apr 8;42(1):84-95. doi: 10.1016/j.molcel.2011.01.030. Mol Cell. 2011. PMID: 21474070 Free PMC article.
Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.
Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Pandolfi PP, Wymann MP, Hirsch E. Ciraolo E, et al. Among authors: wymann mp. Mol Biol Cell. 2010 Mar 1;21(5):704-11. doi: 10.1091/mbc.e09-08-0744. Epub 2010 Jan 6. Mol Biol Cell. 2010. PMID: 20053680 Free PMC article.
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.
Ferguson GJ, Milne L, Kulkarni S, Sasaki T, Walker S, Andrews S, Crabbe T, Finan P, Jones G, Jackson S, Camps M, Rommel C, Wymann M, Hirsch E, Hawkins P, Stephens L. Ferguson GJ, et al. Nat Cell Biol. 2007 Jan;9(1):86-91. doi: 10.1038/ncb1517. Epub 2006 Dec 17. Nat Cell Biol. 2007. PMID: 17173040
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma.
Costa C, Barberis L, Ambrogio C, Manazza AD, Patrucco E, Azzolino O, Neilsen PO, Ciraolo E, Altruda F, Prestwich GD, Chiarle R, Wymann M, Ridley A, Hirsch E. Costa C, et al. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14354-9. doi: 10.1073/pnas.0703175104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720808 Free PMC article.
134 results