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TDP43 autoregulation gives rise to dominant negative isoforms that are tightly controlled by transcriptional and post-translational mechanisms.
Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Miller MR, Bai J, Shahzad S, Nedumaran N, Wieland C, Stewart C, Willey S, Grotewold N, McBride J, Moran JJ, Suryakumar AV, Lucas M, Tessier PM, Ward M, Todd PK, Barmada SJ. Dykstra MM, et al. Among authors: todd pk. Cell Rep. 2025 Jan 8;44(1):115113. doi: 10.1016/j.celrep.2024.115113. Online ahead of print. Cell Rep. 2025. PMID: 39792557 Free article.
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease.
Thomas T, Friedrich M, Rich-Griffin C, Pohin M, Agarwal D, Pakpoor J, Lee C, Tandon R, Rendek A, Aschenbrenner D, Jainarayanan A, Voda A, Siu JHY, Sanches-Peres R, Nee E, Sathananthan D, Kotliar D, Todd P, Kiourlappou M, Gartner L, Ilott N, Issa F, Hester J, Turner J, Nayar S, Mackerodt J, Zhang F, Jonsson A, Brenner M, Raychaudhuri S, Kulicke R, Ramsdell D, Stransky N, Pagliarini R, Bielecki P, Spies N, Marsden B, Taylor S, Wagner A, Klenerman P, Walsh A, Coles M, Jostins-Dean L, Powrie FM, Filer A, Travis S, Uhlig HH, Dendrou CA, Buckley CD. Thomas T, et al. Among authors: todd p. Nat Immunol. 2024 Nov;25(11):2152-2165. doi: 10.1038/s41590-024-01994-8. Epub 2024 Oct 22. Nat Immunol. 2024. PMID: 39438660 Free PMC article.
Shared fate was associated with sustained cooperation during the COVID-19 pandemic.
Guevara Beltran D, Ayers JD, Claessens S, Alcock J, Baciu C, Cronk L, Hudson NM, Hurmuz-Sklias H, Miller G, Tidball K, Van Horn A, Winfrey P, Zarka E, Todd PM, Aktipis A. Guevara Beltran D, et al. Among authors: todd pm. PLoS One. 2024 Sep 26;19(9):e0307829. doi: 10.1371/journal.pone.0307829. eCollection 2024. PLoS One. 2024. PMID: 39325844 Free PMC article.
AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS neurons.
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Willey S, Van Deynze K, Mumm C, Boyle AP, Cortese A, Ndayisaba A, Khurana V, Barmada SJ, Dijkstra AA, Todd PK. Maltby CJ, et al. Among authors: todd pk. Sci Adv. 2024 Sep 6;10(36):eadn2321. doi: 10.1126/sciadv.adn2321. Epub 2024 Sep 4. Sci Adv. 2024. PMID: 39231235 Free PMC article.
Stress granule formation helps to mitigate neurodegeneration.
Glineburg MR, Yildirim E, Gomez N, Rodriguez G, Pak J, Li X, Altheim C, Waksmacki J, McInerney GM, Barmada SJ, Todd PK. Glineburg MR, et al. Among authors: todd pk. Nucleic Acids Res. 2024 Sep 9;52(16):9745-9759. doi: 10.1093/nar/gkae655. Nucleic Acids Res. 2024. PMID: 39106168 Free PMC article.
TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms.
Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Bai J, Shahzad S, Nedumaran J, Wieland C, Stewart C, Willey S, Grotewold N, McBride J, Moran JJ, Suryakumar AV, Lucas M, Tessier P, Ward M, Todd P, Barmada SJ. Dykstra MM, et al. Among authors: todd p. bioRxiv [Preprint]. 2024 Jul 4:2024.07.02.601776. doi: 10.1101/2024.07.02.601776. bioRxiv. 2024. Update in: Cell Rep. 2025 Jan 8;44(1):115113. doi: 10.1016/j.celrep.2024.115113 PMID: 39005384 Free PMC article. Updated. Preprint.
FMR1 Disorders.
Hunter JE, Berry-Kravis E, Hipp H, Todd PK. Hunter JE, et al. Among authors: todd pk. 1998 Jun 16 [updated 2024 May 16]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2025. 1998 Jun 16 [updated 2024 May 16]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2025. PMID: 20301558 Free Books & Documents. Review.
569 results