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Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion.
Richard AM, Webb DL, Goodman JM, Schultz V, Flanagan JN, Getty-Kaushik L, Deeney JT, Yaney GC, Dunaway GA, Berggren PO, Tornheim K. Richard AM, et al. Am J Physiol Endocrinol Metab. 2007 Sep;293(3):E794-801. doi: 10.1152/ajpendo.00168.2007. Epub 2007 Jun 26. Am J Physiol Endocrinol Metab. 2007. PMID: 17595219 Free article.
Mice deficient in phosphofructokinase-M have greatly decreased fat stores.
Getty-Kaushik L, Viereck JC, Goodman JM, Guo Z, LeBrasseur NK, Richard AM, Flanagan JN, Yaney GC, Hamilton JA, Tornheim K. Getty-Kaushik L, et al. Among authors: richard am. Obesity (Silver Spring). 2010 Mar;18(3):434-40. doi: 10.1038/oby.2009.295. Epub 2009 Sep 24. Obesity (Silver Spring). 2010. PMID: 19779479 Free PMC article.
Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.
Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, Brown NF. Perdomo G, et al. Among authors: richard am. J Biol Chem. 2004 Jun 25;279(26):27177-86. doi: 10.1074/jbc.M403566200. Epub 2004 Apr 22. J Biol Chem. 2004. PMID: 15105415 Free article.
115 results