High KA - Search Results

1

Factor VII mutant V154G models a zymogen-like form of factor VIIa.

Toso R, Bernardi F, Tidd T, Pinotti M, Camire RM, Marchetti G, High KA, Pollak ES. Toso R, et al. Among authors: high ka. Biochem J. 2003 Feb 1;369(Pt 3):563-71. doi: 10.1042/BJ20020888. Biochem J. 2003. PMID: 12358603 Free PMC article.

2

A frequent human coagulation Factor VII mutation (A294V, c152) in loop 140s affects the interaction with activators, tissue factor and substrates.

Toso R, Pinotti M, High KA, Pollak ES, Bernardi F. Toso R, et al. Among authors: high ka. Biochem J. 2002 Apr 15;363(Pt 2):411-6. doi: 10.1042/0264-6021:3630411. Biochem J. 2002. PMID: 11931672 Free PMC article.

3

Novel therapeutic approach for hemophilia using gene delivery of an engineered secreted activated Factor VII.

Margaritis P, Arruda VR, Aljamali M, Camire RM, Schlachterman A, High KA. Margaritis P, et al. Among authors: high ka. J Clin Invest. 2004 Apr;113(7):1025-31. doi: 10.1172/JCI20106. J Clin Invest. 2004. PMID: 15057309 Free PMC article.

4

Severe factor VII deficiency due to a mutation disrupting an Sp1 binding site in the factor VII promoter.

Carew JA, Pollak ES, High KA, Bauer KA. Carew JA, et al. Among authors: high ka. Blood. 1998 Sep 1;92(5):1639-45. Blood. 1998. PMID: 9716591 Free article.

5

Severe factor VII deficiency due to a mutation disrupting a hepatocyte nuclear factor 4 binding site in the factor VII promoter.

Arbini AA, Pollak ES, Bayleran JK, High KA, Bauer KA. Arbini AA, et al. Among authors: high ka. Blood. 1997 Jan 1;89(1):176-82. Blood. 1997. PMID: 8978290 Free article.

6

A novel missense mutation responsible for factor VII deficiency in research Beagle colonies.

Callan MB, Aljamali MN, Margaritis P, Griot-Wenk ME, Pollak ES, Werner P, Giger U, High KA. Callan MB, et al. Among authors: high ka. J Thromb Haemost. 2006 Dec;4(12):2616-22. doi: 10.1111/j.1538-7836.2006.02203.x. Epub 2006 Sep 8. J Thromb Haemost. 2006. PMID: 16961583 Free article.

7

Functional characterization of the human factor VII 5'-flanking region.

Pollak ES, Hung HL, Godin W, Overton GC, High KA. Pollak ES, et al. Among authors: high ka. J Biol Chem. 1996 Jan 19;271(3):1738-47. doi: 10.1074/jbc.271.3.1738. J Biol Chem. 1996. PMID: 8576177 Free article.

8

Enhanced gamma-carboxylation of recombinant factor X using a chimeric construct containing the prothrombin propeptide.

Camire RM, Larson PJ, Stafford DW, High KA. Camire RM, et al. Among authors: high ka. Biochemistry. 2000 Nov 21;39(46):14322-9. doi: 10.1021/bi001074q. Biochemistry. 2000. PMID: 11087381

9

Long-term expression of murine activated factor VII is safe, but elevated levels cause premature mortality.

Aljamali MN, Margaritis P, Schlachterman A, Tai SJ, Roy E, Bunte R, Camire RM, High KA. Aljamali MN, et al. Among authors: high ka. J Clin Invest. 2008 May;118(5):1825-34. doi: 10.1172/JCI32878. J Clin Invest. 2008. PMID: 18398505 Free PMC article.

10

Regulation of human coagulation factor X gene expression by GATA-4 and the Sp family of transcription factors.

Hung HL, Pollak ES, Kudaravalli RD, Arruda V, Chu K, High KA. Hung HL, et al. Among authors: high ka. Blood. 2001 Feb 15;97(4):946-51. doi: 10.1182/blood.v97.4.946. Blood. 2001. PMID: 11159521 Free article.

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