Cohen GM - Search Results

1

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

MacFarlane M, Harper N, Snowden RT, Dyer MJ, Barnett GA, Pringle JH, Cohen GM. MacFarlane M, et al. Among authors: cohen gm. Oncogene. 2002 Oct 3;21(44):6809-18. doi: 10.1038/sj.onc.1205853. Oncogene. 2002. PMID: 12360407

2

Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis.

Harper N, Hughes M, MacFarlane M, Cohen GM. Harper N, et al. Among authors: cohen gm. J Biol Chem. 2003 Jul 11;278(28):25534-41. doi: 10.1074/jbc.M303399200. Epub 2003 Apr 29. J Biol Chem. 2003. PMID: 12721308 Free article.

3

Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.

Dewson G, Snowden RT, Almond JB, Dyer MJ, Cohen GM. Dewson G, et al. Among authors: cohen gm. Oncogene. 2003 May 1;22(17):2643-54. doi: 10.1038/sj.onc.1206326. Oncogene. 2003. PMID: 12730678

4

Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.

Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M. Harper N, et al. Among authors: cohen gm. J Biol Chem. 2003 Nov 7;278(45):44338-47. doi: 10.1074/jbc.M307376200. Epub 2003 Aug 14. J Biol Chem. 2003. PMID: 12920112 Free article.

5

TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies.

MacFarlane M, Kohlhaas SL, Sutcliffe MJ, Dyer MJ, Cohen GM. MacFarlane M, et al. Among authors: cohen gm. Cancer Res. 2005 Dec 15;65(24):11265-70. doi: 10.1158/0008-5472.CAN-05-2801. Cancer Res. 2005. PMID: 16357130

6

Inhibition of histone deacetylase class I but not class II is critical for the sensitization of leukemic cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Inoue S, Mai A, Dyer MJ, Cohen GM. Inoue S, et al. Among authors: cohen gm. Cancer Res. 2006 Jul 1;66(13):6785-92. doi: 10.1158/0008-5472.CAN-05-4563. Cancer Res. 2006. PMID: 16818655

7

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.

Natoni A, MacFarlane M, Inoue S, Walewska R, Majid A, Knee D, Stover DR, Dyer MJ, Cohen GM. Natoni A, et al. Among authors: cohen gm. Br J Haematol. 2007 Nov;139(4):568-77. doi: 10.1111/j.1365-2141.2007.06852.x. Epub 2007 Oct 8. Br J Haematol. 2007. PMID: 17922877 Free article.

8

Enhanced Fas-associated death domain recruitment by histone deacetylase inhibitors is critical for the sensitization of chronic lymphocytic leukemia cells to TRAIL-induced apoptosis.

Inoue S, Harper N, Walewska R, Dyer MJ, Cohen GM. Inoue S, et al. Among authors: cohen gm. Mol Cancer Ther. 2009 Nov;8(11):3088-97. doi: 10.1158/1535-7163.MCT-09-0451. Epub 2009 Nov 3. Mol Cancer Ther. 2009. PMID: 19887558

9

Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases.

Harper N, Farrow SN, Kaptein A, Cohen GM, MacFarlane M. Harper N, et al. Among authors: cohen gm. J Biol Chem. 2001 Sep 14;276(37):34743-52. doi: 10.1074/jbc.M105693200. Epub 2001 Jul 18. J Biol Chem. 2001. PMID: 11461927 Free article.

10

Bisindolylmaleimide IX is a potent inducer of apoptosis in chronic lymphocytic leukaemic cells and activates cleavage of Mcl-1.

Snowden RT, Sun XM, Dyer MJ, Cohen GM. Snowden RT, et al. Among authors: cohen gm. Leukemia. 2003 Oct;17(10):1981-9. doi: 10.1038/sj.leu.2403088. Leukemia. 2003. PMID: 14513048

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