Pearl LH - Search Results

1

Backbone resonance assignments of the 25kD N-terminal ATPase domain from the Hsp90 chaperone.

Salek RM, Williams MA, Prodromou C, Pearl LH, Ladbury JE. Salek RM, et al. Among authors: pearl lh. J Biomol NMR. 2002 Aug;23(4):327-8. doi: 10.1023/a:1020268712347. J Biomol NMR. 2002. PMID: 12398355 No abstract available.

2

Structure and functional relationships of Hsp90.

Prodromou C, Pearl LH. Prodromou C, et al. Among authors: pearl lh. Curr Cancer Drug Targets. 2003 Oct;3(5):301-23. doi: 10.2174/1568009033481877. Curr Cancer Drug Targets. 2003. PMID: 14529383 Review.

3

Structure and mechanism of the Hsp90 molecular chaperone machinery.

Pearl LH, Prodromou C. Pearl LH, et al. Annu Rev Biochem. 2006;75:271-94. doi: 10.1146/annurev.biochem.75.103004.142738. Annu Rev Biochem. 2006. PMID: 16756493 Review.

4

Structure, function, and mechanism of the Hsp90 molecular chaperone.

Pearl LH, Prodromou C. Pearl LH, et al. Adv Protein Chem. 2001;59:157-86. doi: 10.1016/s0065-3233(01)59005-1. Adv Protein Chem. 2001. PMID: 11868271 Review. No abstract available.

5

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

Meyer P, Prodromou C, Liao C, Hu B, Roe SM, Vaughan CK, Vlasic I, Panaretou B, Piper PW, Pearl LH. Meyer P, et al. Among authors: pearl lh. EMBO J. 2004 Mar 24;23(6):1402-10. doi: 10.1038/sj.emboj.7600141. EMBO J. 2004. PMID: 15039704 Free PMC article.

6

Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.

Siligardi G, Hu B, Panaretou B, Piper PW, Pearl LH, Prodromou C. Siligardi G, et al. Among authors: pearl lh. J Biol Chem. 2004 Dec 10;279(50):51989-98. doi: 10.1074/jbc.M410562200. Epub 2004 Oct 2. J Biol Chem. 2004. PMID: 15466438 Free article.

7

The Hsp90 molecular chaperone: an open and shut case for treatment.

Pearl LH, Prodromou C, Workman P. Pearl LH, et al. Biochem J. 2008 Mar 15;410(3):439-53. doi: 10.1042/BJ20071640. Biochem J. 2008. PMID: 18290764 Review.

8

Structural-thermodynamic relationships of interactions in the N-terminal ATP-binding domain of Hsp90.

Nilapwar S, Williams E, Fu C, Prodromou C, Pearl LH, Williams MA, Ladbury JE. Nilapwar S, et al. Among authors: pearl lh. J Mol Biol. 2009 Oct 2;392(4):923-36. doi: 10.1016/j.jmb.2009.07.041. Epub 2009 Jul 21. J Mol Biol. 2009. PMID: 19631219

9

Expression and crystallization of the yeast Hsp82 chaperone, and preliminary X-ray diffraction studies of the amino-terminal domain.

Prodromou C, Piper PW, Pearl LH. Prodromou C, et al. Among authors: pearl lh. Proteins. 1996 Aug;25(4):517-22. doi: 10.1002/prot.13. Proteins. 1996. PMID: 8865348

10

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone.

Prodromou C, Roe SM, Piper PW, Pearl LH. Prodromou C, et al. Among authors: pearl lh. Nat Struct Biol. 1997 Jun;4(6):477-82. doi: 10.1038/nsb0697-477. Nat Struct Biol. 1997. PMID: 9187656

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