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Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.
Sánchez-Martín L, Sánchez-Sánchez N, Gutiérrez-López MD, Rojo AI, Vicente-Manzanares M, Pérez-Alvarez MJ, Sánchez-Mateos P, Bustelo XR, Cuadrado A, Sánchez-Madrid F, Rodríguez-Fernández JL, Cabañas C. Sánchez-Martín L, et al. J Biol Chem. 2004 Apr 16;279(16):16194-205. doi: 10.1074/jbc.M400905200. Epub 2004 Feb 11. J Biol Chem. 2004. PMID: 14960575 Free article.
The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9.
Gutiérrez-López MD, Gilsanz A, Yáñez-Mó M, Ovalle S, Lafuente EM, Domínguez C, Monk PN, González-Alvaro I, Sánchez-Madrid F, Cabañas C. Gutiérrez-López MD, et al. Cell Mol Life Sci. 2011 Oct;68(19):3275-92. doi: 10.1007/s00018-011-0639-0. Epub 2011 Mar 2. Cell Mol Life Sci. 2011. PMID: 21365281 Free PMC article.
ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9.
Gilsanz A, Sánchez-Martín L, Gutiérrez-López MD, Ovalle S, Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM, Cabañas C. Gilsanz A, et al. Cell Mol Life Sci. 2013 Feb;70(3):475-93. doi: 10.1007/s00018-012-1132-0. Epub 2012 Sep 30. Cell Mol Life Sci. 2013. PMID: 23052204 Free PMC article.
Functional interplay between tetraspanins and proteases.
Yáñez-Mó M, Gutiérrez-López MD, Cabañas C. Yáñez-Mó M, et al. Cell Mol Life Sci. 2011 Oct;68(20):3323-35. doi: 10.1007/s00018-011-0746-y. Epub 2011 Jun 18. Cell Mol Life Sci. 2011. PMID: 21687991 Free PMC article. Review.
3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) disrupts blood-brain barrier integrity through a mechanism involving P2X7 receptors.
Rubio-Araiz A, Perez-Hernandez M, Urrutia A, Porcu F, Borcel E, Gutierrez-Lopez MD, O'Shea E, Colado MI. Rubio-Araiz A, et al. Among authors: gutierrez lopez md. Int J Neuropsychopharmacol. 2014 Aug;17(8):1243-55. doi: 10.1017/S1461145714000145. Epub 2014 Mar 14. Int J Neuropsychopharmacol. 2014. PMID: 24626059 Free article.
37 results