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Granulocyte-macrophage colony-stimulating factor (GM-CSF) and inflammatory stimuli up-regulate secretion of the soluble GM-CSF receptor in human monocytes: evidence for ectodomain shedding of the cell surface GM-CSF receptor alpha subunit.
Prevost JM, Pelley JL, Zhu W, D'Egidio GE, Beaudry PP, Pihl C, Neely GG, Claret E, Wijdenes J, Brown CB. Prevost JM, et al. Among authors: brown cb. J Immunol. 2002 Nov 15;169(10):5679-88. doi: 10.4049/jimmunol.169.10.5679. J Immunol. 2002. PMID: 12421947
The soluble granulocyte-macrophage colony-stimulating factor receptor's carboxyl-terminal domain mediates retention of the soluble receptor on the cell surface through interaction with the granulocyte-macrophage colony-stimulating factor receptor beta-subunit.
Murray EW, Pihl C, Robbins SM, Prevost J, Mokashi A, Bloomfield SM, Brown CB. Murray EW, et al. Among authors: brown cb. Biochemistry. 1998 Oct 6;37(40):14113-20. doi: 10.1021/bi9802364. Biochemistry. 1998. PMID: 9760247
Lipopolysaccharide-stimulated or granulocyte-macrophage colony-stimulating factor-stimulated monocytes rapidly express biologically active IL-15 on their cell surface independent of new protein synthesis.
Neely GG, Robbins SM, Amankwah EK, Epelman S, Wong H, Spurrell JC, Jandu KK, Zhu W, Fogg DK, Brown CB, Mody CH. Neely GG, et al. Among authors: brown cb. J Immunol. 2001 Nov 1;167(9):5011-7. doi: 10.4049/jimmunol.167.9.5011. J Immunol. 2001. PMID: 11673509
248 results