Dai Y - Search Results

1

Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.

McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. McKinstry R, et al. Among authors: dai y. Cancer Biol Ther. 2002 May-Jun;1(3):243-53. doi: 10.4161/cbt.75. Cancer Biol Ther. 2002. PMID: 12432271 Free article.

2

Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.

Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S. Harvey S, et al. Among authors: dai y. Clin Cancer Res. 2001 Feb;7(2):320-30. Clin Cancer Res. 2001. PMID: 11234887

3

Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.

Dai Y, Yu C, Singh V, Tang L, Wang Z, McInistry R, Dent P, Grant S. Dai Y, et al. Cancer Res. 2001 Jul 1;61(13):5106-15. Cancer Res. 2001. PMID: 11431348

4

The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway.

Decker RH, Dai Y, Grant S. Decker RH, et al. Among authors: dai y. Cell Death Differ. 2001 Jul;8(7):715-24. doi: 10.1038/sj.cdd.4400868. Cell Death Differ. 2001. PMID: 11464216

5

Bryostatin 1 increases 1-beta-D-arabinofuranosylcytosine-induced cytochrome c release and apoptosis in human leukemia cells ectopically expressing Bcl-x(L).

Wang Z, Wang S, Dai Y, Grant S. Wang Z, et al. Among authors: dai y. J Pharmacol Exp Ther. 2002 May;301(2):568-77. doi: 10.1124/jpet.301.2.568. J Pharmacol Exp Ther. 2002. PMID: 11961058

6

Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways.

Cartee L, Smith R, Dai Y, Rahmani M, Rosato R, Almenara J, Dent P, Grant S. Cartee L, et al. Among authors: dai y. Mol Pharmacol. 2002 Jun;61(6):1313-21. doi: 10.1124/mol.61.6.1313. Mol Pharmacol. 2002. PMID: 12021392

7

The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process.

Rahmani M, Dai Y, Grant S. Rahmani M, et al. Among authors: dai y. Exp Cell Res. 2002 Jul 1;277(1):31-47. doi: 10.1006/excr.2002.5548. Exp Cell Res. 2002. PMID: 12061815

8

Loss of the Bcl-2 phosphorylation loop domain is required to protect human myeloid leukemia cells from flavopiridol-mediated mitochondrial damage and apoptosis.

Decker RH, Wang S, Dai Y, Dent P, Grant S. Decker RH, et al. Among authors: dai y. Cancer Biol Ther. 2002 Mar-Apr;1(2):136-44. doi: 10.4161/cbt.58. Cancer Biol Ther. 2002. PMID: 12170773 Free article.

9

Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism.

Dai Y, Landowski TH, Rosen ST, Dent P, Grant S. Dai Y, et al. Blood. 2002 Nov 1;100(9):3333-43. doi: 10.1182/blood-2002-03-0940. Blood. 2002. PMID: 12384435 Free article.

10

Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.

Dai Y, Dent P, Grant S. Dai Y, et al. Cell Cycle. 2002 Mar-Apr;1(2):143-52. Cell Cycle. 2002. PMID: 12429924

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