Delarue M - Search Results

1

Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods.

Manallack DT, Pitt WR, Herdewijn P, Balzarini J, De Clercq E, Sanderson MR, Sohi M, Wien F, Munier-Lehmann H, Haouz A, Delarue M. Manallack DT, et al. Among authors: delarue m. J Enzyme Inhib Med Chem. 2002 Jun;17(3):167-74. doi: 10.1080/14756360290032949. J Enzyme Inhib Med Chem. 2002. PMID: 12443042 Free article.

2

Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis.

Li de la Sierra I, Munier-Lehmann H, Gilles AM, Bârzu O, Delarue M. Li de la Sierra I, et al. Among authors: delarue m. Acta Crystallogr D Biol Crystallogr. 2000 Feb;56(Pt 2):226-8. doi: 10.1107/s0907444999016212. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10666613

3

X-ray structure of TMP kinase from Mycobacterium tuberculosis complexed with TMP at 1.95 A resolution.

Li de la Sierra I, Munier-Lehmann H, Gilles AM, Bârzu O, Delarue M. Li de la Sierra I, et al. Among authors: delarue m. J Mol Biol. 2001 Aug 3;311(1):87-100. doi: 10.1006/jmbi.2001.4843. J Mol Biol. 2001. PMID: 11469859

4

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.

Haouz A, Vanheusden V, Munier-Lehmann H, Froeyen M, Herdewijn P, Van Calenbergh S, Delarue M. Haouz A, et al. Among authors: delarue m. J Biol Chem. 2003 Feb 14;278(7):4963-71. doi: 10.1074/jbc.M209630200. Epub 2002 Nov 25. J Biol Chem. 2003. PMID: 12454011 Free article.

5

Mycobacterium tuberculosis thymidylate kinase: structural studies of intermediates along the reaction pathway.

Fioravanti E, Haouz A, Ursby T, Munier-Lehmann H, Delarue M, Bourgeois D. Fioravanti E, et al. Among authors: delarue m. J Mol Biol. 2003 Apr 11;327(5):1077-92. doi: 10.1016/s0022-2836(03)00202-x. J Mol Biol. 2003. PMID: 12662932

6

Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei.

Delarue M, Duclert-Savatier N, Miclet E, Haouz A, Giganti D, Ouazzani J, Lopez P, Nilges M, Stoven V. Delarue M, et al. J Mol Biol. 2007 Feb 23;366(3):868-81. doi: 10.1016/j.jmb.2006.11.063. Epub 2006 Nov 22. J Mol Biol. 2007. PMID: 17196981

7

Crystal structure of the extracellular domain of a bacterial ligand-gated ion channel.

Nury H, Bocquet N, Le Poupon C, Raynal B, Haouz A, Corringer PJ, Delarue M. Nury H, et al. Among authors: delarue m. J Mol Biol. 2010 Feb 5;395(5):1114-27. doi: 10.1016/j.jmb.2009.11.024. Epub 2009 Nov 13. J Mol Biol. 2010. PMID: 19917292

8

2'-Deoxyribonucleoside phosphoramidate triphosphate analogues as alternative substrates for E. coli polymerase III.

Giraut A, Abu El-Asrar R, Marlière P, Delarue M, Herdewijn P. Giraut A, et al. Among authors: delarue m. Chembiochem. 2012 Nov 5;13(16):2439-44. doi: 10.1002/cbic.201200413. Epub 2012 Sep 28. Chembiochem. 2012. PMID: 23023962

9

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.

Samson C, Legrand P, Tekpinar M, Rozenski J, Abramov M, Holliger P, Pinheiro VB, Herdewijn P, Delarue M. Samson C, et al. Among authors: delarue m. Biomolecules. 2020 Dec 8;10(12):1647. doi: 10.3390/biom10121647. Biomolecules. 2020. PMID: 33302546 Free PMC article.

10

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation.

Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M. Sauguet L, et al. Among authors: delarue m. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):966-71. doi: 10.1073/pnas.1314997111. Epub 2013 Dec 23. Proc Natl Acad Sci U S A. 2014. PMID: 24367074 Free PMC article.

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