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Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.
Tomita T, Tokuhiro S, Hashimoto T, Aiba K, Saido TC, Maruyama K, Iwatsubo T. Tomita T, et al. Among authors: saido tc. J Biol Chem. 1998 Aug 14;273(33):21153-60. doi: 10.1074/jbc.273.33.21153. J Biol Chem. 1998. PMID: 9694871 Free article.
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.
Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, Kiryu-Seo S, Kiyama H, Iwata H, Tomita T, Iwatsubo T, Saido TC. Shirotani K, et al. Among authors: saido tc. J Biol Chem. 2001 Jun 15;276(24):21895-901. doi: 10.1074/jbc.M008511200. Epub 2001 Mar 6. J Biol Chem. 2001. PMID: 11278416 Free article.
[BACE1 and glycosyltransferases].
Kitazume-Kawaguchi S, Hashimoto Y, Saido T. Kitazume-Kawaguchi S, et al. Tanpakushitsu Kakusan Koso. 2003 Jun;48(8 Suppl):984-9. Tanpakushitsu Kakusan Koso. 2003. PMID: 12806999 Review. Japanese. No abstract available.
504 results