Fledelius C - Search Results

1

Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.

Brand CL, Sturis J, Gotfredsen CF, Fleckner J, Fledelius C, Hansen BF, Andersen B, Ye JM, Sauerberg P, Wassermann K. Brand CL, et al. Among authors: fledelius c. Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E841-54. doi: 10.1152/ajpendo.00348.2002. Epub 2002 Dec 10. Am J Physiol Endocrinol Metab. 2003. PMID: 12475752 Free article.

2

Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker rats.

Alemzadeh R, Fledelius C, Bodvarsdottir T, Sturis J. Alemzadeh R, et al. Among authors: fledelius c. Metabolism. 2004 Apr;53(4):441-7. doi: 10.1016/j.metabol.2003.10.027. Metabolism. 2004. PMID: 15045689

3

Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.

Edgerton DS, Scott M, Farmer B, Williams PE, Madsen P, Kjeldsen T, Brand CL, Fledelius C, Nishimura E, Cherrington AD. Edgerton DS, et al. Among authors: fledelius c. JCI Insight. 2019 Feb 26;5(7):e126974. doi: 10.1172/jci.insight.126974. JCI Insight. 2019. PMID: 30830873 Free PMC article.

4

Insulin Delivery Into the Peripheral Circulation: A Key Contributor to Hypoglycemia in Type 1 Diabetes.

Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Allen EJ, Donahue EP, Rivera N, Winnick JJ, Edgerton DS, Nishimura E, Fledelius C, Brand CL, Cherrington AD. Gregory JM, et al. Among authors: fledelius c. Diabetes. 2015 Oct;64(10):3439-51. doi: 10.2337/db15-0071. Epub 2015 Jun 17. Diabetes. 2015. PMID: 26085570 Free PMC article.

5

Peripherally delivered hepatopreferential insulin analog insulin-406 mimics the hypoglycaemia-sparing effect of portal vein human insulin infusion in dogs.

Gregory JM, Kraft G, Scott MF, Neal DW, Farmer B, Smith MS, Hastings JR, Madsen P, Kjeldsen TB, Hostrup S, Brand CL, Fledelius C, Nishimura E, Cherrington AD. Gregory JM, et al. Among authors: fledelius c. Diabetes Obes Metab. 2019 Oct;21(10):2294-2304. doi: 10.1111/dom.13808. Epub 2019 Jul 8. Diabetes Obes Metab. 2019. PMID: 31183936 Free PMC article.

6

Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts.

Hvid H, Blouin MJ, Birman E, Damgaard J, Poulsen F, Fels JJ, Fledelius C, Hansen BF, Pollak M. Hvid H, et al. Among authors: fledelius c. PLoS One. 2013 Nov 18;8(11):e79710. doi: 10.1371/journal.pone.0079710. eCollection 2013. PLoS One. 2013. PMID: 24260289 Free PMC article.

7

Synthesis and pharmacological evaluation of novel cis-3,4-diaryl-hydroxychromanes as high affinity partial agonists for the estrogen receptor.

Bury PS, Christiansen LB, Jacobsen P, Jørgensen AS, Kanstrup A, Naerum L, Bain S, Fledelius C, Gissel B, Hansen BS, Korsgaard N, Thorpe SM, Wassermann K. Bury PS, et al. Among authors: fledelius c. Bioorg Med Chem. 2002 Jan;10(1):125-45. doi: 10.1016/s0968-0896(01)00257-7. Bioorg Med Chem. 2002. PMID: 11738615

8

Treatment of diabetic rats with insulin or a synthetic insulin receptor agonist peptide leads to divergent metabolic responses.

Frikke-Schmidt H, Pedersen TÅ, Fledelius C, Olsen GS, Bouman SD, Fitch M, Hellerstein M. Frikke-Schmidt H, et al. Among authors: fledelius c. Diabetes. 2015 Mar;64(3):1057-66. doi: 10.2337/db14-0914. Epub 2014 Oct 14. Diabetes. 2015. PMID: 25315006

9

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice.

Gelling RW, Du XQ, Dichmann DS, Romer J, Huang H, Cui L, Obici S, Tang B, Holst JJ, Fledelius C, Johansen PB, Rossetti L, Jelicks LA, Serup P, Nishimura E, Charron MJ. Gelling RW, et al. Among authors: fledelius c. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1438-43. doi: 10.1073/pnas.0237106100. Epub 2003 Jan 24. Proc Natl Acad Sci U S A. 2003. PMID: 12552113 Free PMC article.

10

Open flow microperfusion: pharmacokinetics of human insulin and insulin detemir in the interstitial fluid of subcutaneous adipose tissue.

Höfferer C, Tutkur D, Fledelius C, Brand CL, Alsted TJ, Damgaard J, Nishimura E, Jeppesen CB, Mautner SI, Pieber TR, Sinner F. Höfferer C, et al. Among authors: fledelius c. Diabetes Obes Metab. 2015 Feb;17(2):121-7. doi: 10.1111/dom.12394. Epub 2014 Oct 26. Diabetes Obes Metab. 2015. PMID: 25243522

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