de Pascual-Teresa B - Search Results

1

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle MF, Yuste M. Braña MF, et al. J Med Chem. 2002 Dec 19;45(26):5813-6. doi: 10.1021/jm020950q. J Med Chem. 2002. PMID: 12477366

2

Molecular dynamics simulations of the bis-intercalated complexes of ditercalinium and Flexi-Di with the hexanucleotide d(GCGCGC)2: theoretical analysis of the interaction and rationale for the sequence binding specificity.

de Pascual-Teresa B, Gallego J, Ortiz AR, Gago F. de Pascual-Teresa B, et al. J Med Chem. 1996 Nov 22;39(24):4810-24. doi: 10.1021/jm9604179. J Med Chem. 1996. PMID: 8941395

3

Assessment of solvation effects on calculated binding affinity differences: trypsin inhibition by flavonoids as a model system for congeneric series.

Checa A, Ortiz AR, de Pascual-Teresa B, Gago F. Checa A, et al. J Med Chem. 1997 Dec 5;40(25):4136-45. doi: 10.1021/jm970245v. J Med Chem. 1997. PMID: 9406602

4

Intercalators as anticancer drugs.

Braña MF, Cacho M, Gradillas A, de Pascual-Teresa B, Ramos A. Braña MF, et al. Curr Pharm Des. 2001 Nov;7(17):1745-80. doi: 10.2174/1381612013397113. Curr Pharm Des. 2001. PMID: 11562309 Review.

5

Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines.

Braña MF, Casarrubios L, Domínguez G, Fernández C, Pérez JM, Quiroga AG, Navarro-Ranninger C, de Pascual-Teresa B. Braña MF, et al. Eur J Med Chem. 2002 Apr;37(4):301-13. doi: 10.1016/s0223-5234(02)01348-x. Eur J Med Chem. 2002. PMID: 11960665

6

Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins.

López-Pérez JL, del Olmo E, de Pascual-Teresa B, Abad A, San Feliciano A. López-Pérez JL, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1283-6. doi: 10.1016/j.bmcl.2003.12.039. Bioorg Med Chem Lett. 2004. PMID: 14980682

7

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Domínguez MT, Pozuelo JM, Abradelo C, Rey-Stolle MF, Yuste M, Báñez-Coronel M, Lacal JC. Braña MF, et al. J Med Chem. 2004 Mar 11;47(6):1391-9. doi: 10.1021/jm0308850. J Med Chem. 2004. PMID: 14998328

8

Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2.

Braña MF, García ML, López B, de Pascual-Teresa B, Ramos A, Pozuelo JM, Domínguez MT. Braña MF, et al. Org Biomol Chem. 2004 Jul 7;2(13):1864-71. doi: 10.1039/b403052d. Epub 2004 Jun 16. Org Biomol Chem. 2004. PMID: 15227538

9

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities.

Julián M, Cacho M, García MA, Martín-Santamaría S, de Pascual-Teresa B, Ramos A, Martínez A, Cuttitta F. Julián M, et al. Eur J Med Chem. 2005 Aug;40(8):737-50. doi: 10.1016/j.ejmech.2004.10.016. Eur J Med Chem. 2005. PMID: 15927308 Review.

10

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin.

García MA, Martín-Santamaría S, Cacho M, de la Llave FM, Julián M, Martínez A, de Pascual-Teresa B, Ramos A. García MA, et al. J Med Chem. 2005 Jun 16;48(12):4068-75. doi: 10.1021/jm050021+. J Med Chem. 2005. PMID: 15943480

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