Wiley HS - Search Results

1

Computational modeling of the EGF-receptor system: a paradigm for systems biology.

Wiley HS, Shvartsman SY, Lauffenburger DA. Wiley HS, et al. Trends Cell Biol. 2003 Jan;13(1):43-50. doi: 10.1016/s0962-8924(02)00009-0. Trends Cell Biol. 2003. PMID: 12480339 Review.

2

The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor.

Wiley HS, Herbst JJ, Walsh BJ, Lauffenburger DA, Rosenfeld MG, Gill GN. Wiley HS, et al. J Biol Chem. 1991 Jun 15;266(17):11083-94. J Biol Chem. 1991. PMID: 1645724 Free article.

3

Molecular/cell engineering approach to autocrine ligand control of cell function.

Lauffenburger DA, Forsten KE, Will B, Wiley HS. Lauffenburger DA, et al. Among authors: wiley hs. Ann Biomed Eng. 1995 May-Jun;23(3):208-15. doi: 10.1007/BF02584423. Ann Biomed Eng. 1995. PMID: 7631977 Review.

4

Regulation of postendocytic trafficking of the epidermal growth factor receptor through endosomal retention.

Herbst JJ, Opresko LK, Walsh BJ, Lauffenburger DA, Wiley HS. Herbst JJ, et al. Among authors: wiley hs. J Biol Chem. 1994 Apr 29;269(17):12865-73. J Biol Chem. 1994. PMID: 8175702 Free article.

5

Postendocytic trafficking of epidermal growth factor-receptor complexes is mediated through saturable and specific endosomal interactions.

French AR, Sudlow GP, Wiley HS, Lauffenburger DA. French AR, et al. Among authors: wiley hs. J Biol Chem. 1994 Jun 3;269(22):15749-55. J Biol Chem. 1994. PMID: 8195228 Free article.

6

Engineering epidermal growth factor for enhanced mitogenic potency.

Reddy CC, Niyogi SK, Wells A, Wiley HS, Lauffenburger DA. Reddy CC, et al. Among authors: wiley hs. Nat Biotechnol. 1996 Dec;14(13):1696-9. doi: 10.1038/nbt1296-1696. Nat Biotechnol. 1996. PMID: 9634854

7

Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization.

Wiley HS, Woolf MF, Opresko LK, Burke PM, Will B, Morgan JR, Lauffenburger DA. Wiley HS, et al. J Cell Biol. 1998 Nov 30;143(5):1317-28. doi: 10.1083/jcb.143.5.1317. J Cell Biol. 1998. PMID: 9832559 Free PMC article.

8

Real-time quantitative measurement of autocrine ligand binding indicates that autocrine loops are spatially localized.

Lauffenburger DA, Oehrtman GT, Walker L, Wiley HS. Lauffenburger DA, et al. Among authors: wiley hs. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15368-73. doi: 10.1073/pnas.95.26.15368. Proc Natl Acad Sci U S A. 1998. PMID: 9860975 Free PMC article.

9

Effect of epidermal growth factor receptor internalization on regulation of the phospholipase C-gamma1 signaling pathway.

Haugh JM, Schooler K, Wells A, Wiley HS, Lauffenburger DA. Haugh JM, et al. Among authors: wiley hs. J Biol Chem. 1999 Mar 26;274(13):8958-65. doi: 10.1074/jbc.274.13.8958. J Biol Chem. 1999. PMID: 10085141 Free article.

10

Escape of autocrine ligands into extracellular medium: experimental test of theoretical model predictions.

Oehrtman GT, Wiley HS, Lauffenburger DA. Oehrtman GT, et al. Among authors: wiley hs. Biotechnol Bioeng. 1998 Mar 5;57(5):571-82. Biotechnol Bioeng. 1998. PMID: 10099236

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