Kirkovsky L - Search Results

1

Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

Yin D, He Y, Perera MA, Hong SS, Marhefka C, Stourman N, Kirkovsky L, Miller DD, Dalton JT. Yin D, et al. Among authors: kirkovsky l. Mol Pharmacol. 2003 Jan;63(1):211-23. doi: 10.1124/mol.63.1.211. Mol Pharmacol. 2003. PMID: 12488554

2

Pharmacology, pharmacokinetics, and metabolism of acetothiolutamide, a novel nonsteroidal agonist for the androgen receptor.

Yin D, Xu H, He Y, Kirkovsky LI, Miller DD, Dalton JT. Yin D, et al. J Pharmacol Exp Ther. 2003 Mar;304(3):1323-33. doi: 10.1124/jpet.102.040832. J Pharmacol Exp Ther. 2003. PMID: 12604713

3

Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor.

He Y, Yin D, Perera M, Kirkovsky L, Stourman N, Li W, Dalton JT, Miller DD. He Y, et al. Among authors: kirkovsky l. Eur J Med Chem. 2002 Aug;37(8):619-34. doi: 10.1016/s0223-5234(02)01335-1. Eur J Med Chem. 2002. PMID: 12161060

4

Affinity labeling of the androgen receptor with nonsteroidal chemoaffinity ligands.

Mukherjee A, Kirkovsky LI, Kimura Y, Marvel MM, Miller DD, Dalton JT. Mukherjee A, et al. Among authors: kirkovsky li. Biochem Pharmacol. 1999 Oct 15;58(8):1259-67. doi: 10.1016/s0006-2952(99)00218-x. Biochem Pharmacol. 1999. PMID: 10487527

5

Enantioselective binding of Casodex to the androgen receptor.

Mukherjee A, Kirkovsky L, Yao XT, Yates RC, Miller DD, Dalton JT. Mukherjee A, et al. Among authors: kirkovsky l. Xenobiotica. 1996 Feb;26(2):117-22. doi: 10.3109/00498259609046693. Xenobiotica. 1996. PMID: 8867996

6

Discovery of nonsteroidal androgens.

Dalton JT, Mukherjee A, Zhu Z, Kirkovsky L, Miller DD. Dalton JT, et al. Among authors: kirkovsky l. Biochem Biophys Res Commun. 1998 Mar 6;244(1):1-4. doi: 10.1006/bbrc.1998.8209. Biochem Biophys Res Commun. 1998. PMID: 9514878

7

Chiral nonsteroidal affinity ligands for the androgen receptor. 1. Bicalutamide analogues bearing electrophilic groups in the B aromatic ring.

Kirkovsky L, Mukherjee A, Yin D, Dalton JT, Miller DD. Kirkovsky L, et al. J Med Chem. 2000 Feb 24;43(4):581-90. doi: 10.1021/jm990027x. J Med Chem. 2000. PMID: 10691684

8

Homology modeling using multiple molecular dynamics simulations and docking studies of the human androgen receptor ligand binding domain bound to testosterone and nonsteroidal ligands.

Marhefka CA, Moore BM 2nd, Bishop TC, Kirkovsky L, Mukherjee A, Dalton JT, Miller DD. Marhefka CA, et al. Among authors: kirkovsky l. J Med Chem. 2001 May 24;44(11):1729-40. doi: 10.1021/jm0005353. J Med Chem. 2001. PMID: 11356108

9

Synthesis of irreversibly binding bicalutamide analogs for imaging studies.

Nair VA, Mustafa SM, Mohler ML, Yang J, Kirkovsky LI, Dalton JT, Miller DD. Nair VA, et al. Among authors: kirkovsky li. Tetrahedron Lett. 2005 Jul 11;46(28):4821-4823. doi: 10.1016/j.tetlet.2005.04.143. Tetrahedron Lett. 2005. PMID: 18079986 Free PMC article.

10

Discovery of ANA975: an oral prodrug of the TLR-7 agonist isatoribine.

Xiang AX, Webber SE, Kerr BM, Rueden EJ, Lennox JR, Haley GJ, Wang T, Ng JS, Herbert MR, Clark DL, Banh VN, Li W, Fletcher SP, Steffy KR, Bartkowski DM, Kirkovsky LI, Bauman LA, Averett DR. Xiang AX, et al. Among authors: kirkovsky li. Nucleosides Nucleotides Nucleic Acids. 2007;26(6-7):635-40. doi: 10.1080/15257770701490472. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066870 Clinical Trial.

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