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Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG. Chepurny OG, et al. Among authors: schwede f. J Biol Chem. 2009 Apr 17;284(16):10728-36. doi: 10.1074/jbc.M900166200. Epub 2009 Feb 25. J Biol Chem. 2009. PMID: 19244230 Free PMC article.
PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG. Chepurny OG, et al. Among authors: schwede f. Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E622-33. doi: 10.1152/ajpendo.00630.2009. Epub 2009 Dec 15. Am J Physiol Endocrinol Metab. 2010. PMID: 20009023 Free PMC article.
cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.
Christensen AE, Selheim F, de Rooij J, Dremier S, Schwede F, Dao KK, Martinez A, Maenhaut C, Bos JL, Genieser HG, Døskeland SO. Christensen AE, et al. Among authors: schwede f. J Biol Chem. 2003 Sep 12;278(37):35394-402. doi: 10.1074/jbc.M302179200. Epub 2003 Jun 20. J Biol Chem. 2003. PMID: 12819211 Free article.
98 results