The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Zhao W, Yuan Q, Qian J, Waggoner JR, Pathak A, Chu G, Mitton B, Sun X, Jin J, Braz JC, Hahn HS, Marreez Y, Syed F, Pollesello P, Annila A, Wang HS, Schultz Jel J, Molkentin JD, Liggett SB, Dorn GW 2nd, Kranias EG.
Zhao W, et al. Among authors: chu g.
Circulation. 2006 Feb 21;113(7):995-1004. doi: 10.1161/CIRCULATIONAHA.105.583351. Epub 2006 Feb 13.
Circulation. 2006.
PMID: 16476846