Wang X - Search Results

1

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway.

Jiang X, Kim HE, Shu H, Zhao Y, Zhang H, Kofron J, Donnelly J, Burns D, Ng SC, Rosenberg S, Wang X. Jiang X, et al. Among authors: wang x. Science. 2003 Jan 10;299(5604):223-6. doi: 10.1126/science.1076807. Science. 2003. PMID: 12522243

2

PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1.

Kim HE, Jiang X, Du F, Wang X. Kim HE, et al. Among authors: wang x. Mol Cell. 2008 Apr 25;30(2):239-47. doi: 10.1016/j.molcel.2008.03.014. Mol Cell. 2008. PMID: 18439902 Free article.

3

Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.

Kim HE, Du F, Fang M, Wang X. Kim HE, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17545-50. doi: 10.1073/pnas.0507900102. Epub 2005 Oct 26. Proc Natl Acad Sci U S A. 2005. PMID: 16251271 Free PMC article.

4

R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway.

Liu Q, Rand TA, Kalidas S, Du F, Kim HE, Smith DP, Wang X. Liu Q, et al. Among authors: wang x. Science. 2003 Sep 26;301(5641):1921-5. doi: 10.1126/science.1088710. Science. 2003. PMID: 14512631

5

Cytochrome C-mediated apoptosis.

Jiang X, Wang X. Jiang X, et al. Among authors: wang x. Annu Rev Biochem. 2004;73:87-106. doi: 10.1146/annurev.biochem.73.011303.073706. Annu Rev Biochem. 2004. PMID: 15189137 Review.

6

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death.

Li L, Thomas RM, Suzuki H, De Brabander JK, Wang X, Harran PG. Li L, et al. Among authors: wang x. Science. 2004 Sep 3;305(5689):1471-4. doi: 10.1126/science.1098231. Science. 2004. PMID: 15353805

7

Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

Acehan D, Jiang X, Morgan DG, Heuser JE, Wang X, Akey CW. Acehan D, et al. Among authors: wang x. Mol Cell. 2002 Feb;9(2):423-32. doi: 10.1016/s1097-2765(02)00442-2. Mol Cell. 2002. PMID: 11864614 Free article.

8

TNF-alpha induces two distinct caspase-8 activation pathways.

Wang L, Du F, Wang X. Wang L, et al. Among authors: wang x. Cell. 2008 May 16;133(4):693-703. doi: 10.1016/j.cell.2008.03.036. Cell. 2008. PMID: 18485876 Free article.

9

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation.

Nijhawan D, Fang M, Traer E, Zhong Q, Gao W, Du F, Wang X. Nijhawan D, et al. Among authors: wang x. Genes Dev. 2003 Jun 15;17(12):1475-86. doi: 10.1101/gad.1093903. Epub 2003 Jun 3. Genes Dev. 2003. PMID: 12783855 Free PMC article.

10

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis.

Zhong Q, Gao W, Du F, Wang X. Zhong Q, et al. Among authors: wang x. Cell. 2005 Jul 1;121(7):1085-95. doi: 10.1016/j.cell.2005.06.009. Cell. 2005. PMID: 15989957 Free article.

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