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Neuritic growth impairment and cell death by unconjugated bilirubin is mediated by NO and glutamate, modulated by microglia, and prevented by glycoursodeoxycholic acid and interleukin-10.
Silva SL, Vaz AR, Diógenes MJ, van Rooijen N, Sebastião AM, Fernandes A, Silva RF, Brites D. Silva SL, et al. Among authors: diogenes mj. Neuropharmacology. 2012 Jun;62(7):2398-408. doi: 10.1016/j.neuropharm.2012.02.002. Epub 2012 Feb 13. Neuropharmacology. 2012. PMID: 22361233
Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.
Nunes MJ, Carvalho AN, Reis J, Costa D, Moutinho M, Mateus J, Mendes de Almeida R, Brito S, Risso D, Nunes S, Castro-Caldas M, Gama MJ, Rodrigues CMP, Xapelli S, Diógenes MJ, Cartier N, Chali F, Piguet F, Rodrigues E. Nunes MJ, et al. Among authors: diogenes mj. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):166993. doi: 10.1016/j.bbadis.2023.166993. Epub 2023 Dec 22. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38142760 Free article.
The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer's Disease Pathophysiology.
Belo RF, Martins MLF, Shvachiy L, Costa-Coelho T, de Almeida-Borlido C, Fonseca-Gomes J, Neves V, Vicente Miranda H, Outeiro TF, Coelho JE, Xapelli S, Valente CA, Heras M, Bardaji E, Castanho MARB, Diógenes MJ, Sebastião AM. Belo RF, et al. Among authors: diogenes mj. Front Pharmacol. 2020 Jul 9;11:985. doi: 10.3389/fphar.2020.00985. eCollection 2020. Front Pharmacol. 2020. PMID: 32733240 Free PMC article.
65 results