Diller D - Search Results

1

Targeting signal transduction with large combinatorial collections.

Auld DS, Diller D, Ho KK. Auld DS, et al. Among authors: diller d. Drug Discov Today. 2002 Dec 15;7(24):1206-13. doi: 10.1016/s1359-6446(02)02530-8. Drug Discov Today. 2002. PMID: 12547003 Review.

2

The synergy between combinatorial chemistry and high-throughput screening.

Diller DJ. Diller DJ. Curr Opin Drug Discov Devel. 2008 May;11(3):346-55. Curr Opin Drug Discov Devel. 2008. PMID: 18428088 Review.

3

2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.

Cole AG, Bohnstedt AC, Paradkar V, Kingsbury C, Quintero JG, Park H, Lu Y, You M, Neagu I, Diller DJ, Letourneau JJ, Shao Y, James RA, Riviello CM, Ho KK, Lin TH, Wang B, Appell KC, Sills M, Quadros E, Kimble EF, Ohlmeyer MH, Webb ML. Cole AG, et al. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6788-92. doi: 10.1016/j.bmcl.2009.09.080. Epub 2009 Sep 25. Bioorg Med Chem Lett. 2009. PMID: 19836234

4

Computation of the physio-chemical properties and data mining of large molecular collections.

Cheng A, Diller DJ, Dixon SL, Egan WJ, Lauri G, Merz KM Jr. Cheng A, et al. J Comput Chem. 2002 Jan 15;23(1):172-83. doi: 10.1002/jcc.1164. J Comput Chem. 2002. PMID: 11913384

5

Characterization of chemical libraries for luciferase inhibitory activity.

Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J. Auld DS, et al. J Med Chem. 2008 Apr 24;51(8):2372-86. doi: 10.1021/jm701302v. Epub 2008 Mar 26. J Med Chem. 2008. PMID: 18363348

6

Successful screening of large encoded combinatorial libraries leading to the discovery of novel p38 MAP kinase inhibitors.

Metzger A, Diller DJ, Lin TH, Henderson I, Webb ML. Metzger A, et al. Comb Chem High Throughput Screen. 2006 Jun;9(5):351-8. doi: 10.2174/138620706777452384. Comb Chem High Throughput Screen. 2006. PMID: 16787148

7

Use of catalyst pharmacophore models for screening of large combinatorial libraries.

Hecker EA, Duraiswami C, Andrea TA, Diller DJ. Hecker EA, et al. J Chem Inf Comput Sci. 2002 Sep-Oct;42(5):1204-11. doi: 10.1021/ci020368a. J Chem Inf Comput Sci. 2002. PMID: 12377010

8

High throughput docking for library design and library prioritization.

Diller DJ, Merz KM Jr. Diller DJ, et al. Proteins. 2001 May 1;43(2):113-24. doi: 10.1002/1097-0134(20010501)43:2<113::aid-prot1023>3.0.co;2-t. Proteins. 2001. PMID: 11276081

9

The different strategies for designing GPCR and kinase targeted libraries.

Lowrie JF, Delisle RK, Hobbs DW, Diller DJ. Lowrie JF, et al. Among authors: diller dj. Comb Chem High Throughput Screen. 2004 Aug;7(5):495-510. doi: 10.2174/1386207043328625. Comb Chem High Throughput Screen. 2004. PMID: 15320714 Review.

10

Kinases, homology models, and high throughput docking.

Diller DJ, Li R. Diller DJ, et al. J Med Chem. 2003 Oct 23;46(22):4638-47. doi: 10.1021/jm020503a. J Med Chem. 2003. PMID: 14561083

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