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22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion.
Koldamova RP, Lefterov IM, Ikonomovic MD, Skoko J, Lefterov PI, Isanski BA, DeKosky ST, Lazo JS. Koldamova RP, et al. Among authors: ikonomovic md. J Biol Chem. 2003 Apr 11;278(15):13244-56. doi: 10.1074/jbc.M300044200. Epub 2003 Jan 22. J Biol Chem. 2003. PMID: 12547833 Free article.
Plasma Glial Fibrillary Acidic Protein Is Associated with 18F-SMBT-1 PET: Two Putative Astrocyte Reactivity Biomarkers for Alzheimer's Disease.
Chatterjee P, Doré V, Pedrini S, Krishnadas N, Thota R, Bourgeat P, Ikonomovic MD, Rainey-Smith SR, Burnham SC, Fowler C, Taddei K, Mulligan R, Ames D, Masters CL, Fripp J, Rowe CC, Martins RN, Villemagne VL; The AIBL Research Group. Chatterjee P, et al. Among authors: ikonomovic md. J Alzheimers Dis. 2023;92(2):615-628. doi: 10.3233/JAD-220908. J Alzheimers Dis. 2023. PMID: 36776057 Free PMC article.
Astrocyte reactivity influences the association of amyloid-β and tau biomarkers in preclinical Alzheimer's disease.
Pascoal T, Bellaver B, Povala G, Ferreira P, Ferrari-Souza JP, Leffa D, Lussier F, Benedet A, Ashton N, Triana-Baltzerz G, Kolbzh H, Tissot C, Therriault J, Servaes S, Stevenson J, Rahmouni N, Lopez O, Tudorascu D, Villemagne V, Ikonomovic M, Gauthier S, Zimmer E, Zetterberg H, Blennow K, Aizenstein H, Klunk W, Snitz B, Maki P, Thurston R, Cohen A, Ganguli M, Karikari T, Rosa-Neto P. Pascoal T, et al. Res Sq [Preprint]. 2023 Feb 1:rs.3.rs-2507179. doi: 10.21203/rs.3.rs-2507179/v1. Res Sq. 2023. Update in: Nat Med. 2023 Jul;29(7):1775-1781. doi: 10.1038/s41591-023-02380-x PMID: 36778243 Free PMC article. Updated. Preprint.
A Neuropathology Case Report of a Woman with Down Syndrome who Remained Cognitively Stable.
Liou JJ, Lou J, Nakagiri J, Yong W, Hom CL, Doran EW, Totoiu M, Lott I, Mapstone M, Keator DB, Brickman AM, Wright S, Nelson B, Lai F, Xicota L, Dang LT, Li J, Santini T, Mettenburg JM, Ikonomovic MD, Kofler J, Ibrahim T, Head E; Alzheimer Biomarker Consortium - Down Syndrome. Liou JJ, et al. Among authors: ikonomovic md. medRxiv [Preprint]. 2024 Jun 3:2024.06.01.24308050. doi: 10.1101/2024.06.01.24308050. medRxiv. 2024. PMID: 38883742 Free PMC article. Preprint.
Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study.
Boerwinkle AH, Gordon BA, Wisch J, Flores S, Henson RL, Butt OH, McKay N, Chen CD, Benzinger TLS, Fagan AM, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, O'Bryant S, Lai F, Rosas HD, Lee JH, Silverman W, Brickman AM, Chhatwal JP, Cruchaga C, Perrin RJ, Xiong C, Hassenstab J, McDade E, Bateman RJ, Ances BM; Alzheimer's Biomarker Consortium-Down Syndrome; Dominantly Inherited Alzheimer Network. Boerwinkle AH, et al. Lancet Neurol. 2023 Jan;22(1):55-65. doi: 10.1016/S1474-4422(22)00408-2. Lancet Neurol. 2023. PMID: 36517172 Free PMC article.
160 results